Results 61 to 70 of about 13,240,817 (334)
FEBS Letters, EarlyView.UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg +2 more
wiley +1 more source
Designing for e-Social Action An Application Taxonomy [PDF]
, 2009 In this paper, we present a taxonomy for understanding designs and designing of Information & Communication Technologies (ICT) in the field of ‘Social Action’.
Dearden, Andy, Light, Ann
core
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Engaging Students and Faculty in the Evaluation of a USMLE Review Product: Implications for Library Collection Development [PDF]
, 2016 Introduction: Study materials for USMLE exams are some of the most commonly requested materials at Dana Medical Library. In Fall 2015, the Dana Medical Library received several student requests for online USMLE preparation materials.
Light, Jeanene, Stokes, Alice
core +1 more source
Liinc em Revista, 2017 RESUMO Em outubro de 2915, organizamos uma oficina para 80 pesquisadores e praticantes envolvidos em makerspaces na Europa. Nosso objetivo era explorar como os makerspaces podem fomentar desenvolvimento sustentável.
Adrian Smith, Ann Light
doaj +1 more source
FEBS Letters, EarlyView.To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche +2 more
wiley +1 more source
Brokering between heads and hearts: an analysis of designing for social change [PDF]
, 2009 This paper describes a fluid and responsive design process identified among certain practitioners involved in solving social problems or inspiring social change.
Light, Ann, Miskelly, C.
core
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
User resistance strategies and the problems of blanket prescriptions: a case study of resistance success [PDF]
, 2006 There is a growing body of research on resistance in IS projects, a good deal of which focuses on strategies for overcoming resistance. However, within this strand of research, it appears that there is a ‘blanket prescription’ approach that does not ...
Griffiths, M, Light, BA
core +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source