Results 91 to 100 of about 8,570,567 (357)

High-intensity ultrasound of chicken myofibrillar protein under reduced-salt conditions: effect on emulsifying and interfacial properties

Food Science of Animal Products
In this study, the effects of high-intensity ultrasound (HIU, frequency 20 kHz, amplitude 60%, power 450 W) for 0, 6, and 9 min on the emulsifying properties of chicken myofibrillar protein (MP) under different NaCl concentrations (0.2, 0.3, 0.4, and 0.5
Linmeng Wang, Yanfang Zhou, Qing Yang, Lei Fu, Ke Li, Yanhong Bai   +5 more
doaj   +1 more source

Encouraging impact of doxycycline on early mortality in cardiac light chain (AL) amyloidosis

Blood Cancer Journal, 2017
Encouraging impact of doxycycline on early mortality in cardiac light chain (AL ...
A. Wechalekar, C. Whelan
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Tuning oxidative stability and digestibility of frozen myofibrillar protein: A combined magnetic field and pH-shifting approach

Food Chemistry: X
This study investigated the synergistic effects of magnetic field (MF) and pH-shifting (pH 9–11) on the oxidative stability and in vitro digestibility of frozen denatured myofibrillar protein (MP).
Bo Chen, Shanshan Huangfu, Jiayi Cai, Wen Nie, Ke Li, Yu Wang, Yanhong Bai   +6 more
doaj   +1 more source

Risk Management: Rethinking Fashion Supply Chain Management for Multinational Corporations in Light of the COVID-19 Outbreak

, 2020
Through an international business risk management lens, the widespread and catalytic implications of the 2020 COVID-19 pandemic on the supply chains (SCs) of fashion multinational corporations (MNC) are analyzed to contribute to existing research on ...
M. McMaster, C. Nettleton, C. Tom, Belanda Xu, Cheng Cao, Ping Qiao   +5 more
semanticscholar   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

The role of notch signaling pathway in cancer: mechanistic insights, therapeutic potential, and clinical progress

Frontiers in Immunology
This article presents a comprehensive literature review on the role of the Notch signaling pathway in cancer and its molecular mechanisms. The Notch signaling pathway plays an important role in various types of cancer by regulating key biological ...
Haokun Zhang, Haokun Zhang, Haokun Zhang, Wang Hang, Wang Hang, Wang Hang, ZhaoHui Jing, ZhaoHui Jing, ZhaoHui Jing, Bingyan Liu, Bingyan Liu, Bingyan Liu, Xiaoxiao Wang, Xiaoxiao Wang, Xiaoxiao Wang, Yilin Li, Yilin Li, Yilin Li, Huomin Luo, Huomin Luo, Huomin Luo, Huilin Lv, Huilin Lv, Huilin Lv, Xingyue Tao, Xingyue Tao, Xingyue Tao, Peter Timashev, Yuzhen Li, Peifeng Li, Peifeng Li, Peifeng Li   +31 more
doaj   +1 more source

Analysis of the conditional mutual information in ballistic and diffusive non-equilibrium steady-states [PDF]

, 2019
The conditional mutual information (CMI) $\mathcal{I}(A\! : \! C|B)$ quantifies the amount of correlations shared between $A$ and $C$ \emph{given} $B$.
Adesso, Gerardo, Goold, John, Landi, Gabriel T., Malouf, William T. B.   +3 more
core   +3 more sources

Cell Damage in Light Chain Amyloidosis

Journal of Biological Chemistry, 2016
Light chain (AL) amyloidosis is an incurable human disease characterized by the misfolding, aggregation, and systemic deposition of amyloid composed of immunoglobulin light chains (LC).
Marta Marin-Argany, Yi Lin, Pinaki Misra, Angela D. Williams, J. Wall, Kyle G. Howell, Laura R. Elsbernd, Megan McClure, M. Ramirez-Alvarado   +8 more
semanticscholar   +1 more source