Results 191 to 200 of about 8,570,567 (357)

Plasma Glial Fibrillary Acidic Protein Correlates With Brain Metal Burden in Wilson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuroinflammation driven by extracellular copper contributes to neuronal damage in Wilson's disease (WD). This study investigated the relationship between brain metal burden and peripheral neuroinflammation markers in WD. Methods We conducted a cross‐sectional study involving 89 participants, including patients with WD (n = 63 ...
Sung‐Pin Fan, Ya‐Fang Chen, Cheng‐Hsuan Li, Yih‐Chih Kuo, Ni‐Chung Lee, Yin‐Hsiu Chien, Wuh‐Liang Hwu, Tai‐Chung Tseng, Tung‐Hung Su, Chien‐Ting Hsu, Huey‐Ling Chen, Chin‐Hsien Lin, Yen‐Hsuan Ni   +12 more
wiley   +1 more source

Comparison of three analytical platforms for quantification of the neurofilament light chain in blood samples: ELISA, electrochemiluminescence immunoassay and Simoa

Clinical Chemistry and Laboratory Medicine, 2016
J. Kuhle, Christian Barro, U. Andreasson, T. Derfuss, R. Lindberg, Å. Sandelius, V. Liman, N. Norgren, K. Blennow, H. Zetterberg   +9 more
semanticscholar   +1 more source

Two distinct factor-binding DNA elements in cardiac myosin light chain 2 gene are essential for repression of its expression in skeletal muscle. Isolation of a cDNA clone for repressor protein Nished.

, 2002
Manya Dhar, Eduardo M. Mascareno, M. A. Q. Siddiqui   +2 more
openalex   +1 more source

Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plus-end-directed motor [PDF]

, 2002
Herm-Götz, Angelika, Weiss Stefan, Stratmann, Rolf, Fujita-Becker, Setsuko, Ruff, Christine, Meyhöfer, Edgar, Soldati Thierry, Manstein, Dietmar J., Geeves, Michael A., Soldati, Dominique, Herm-Götz, Angelika, Meyhöfer, Edgar   +11 more
openalex   +1 more source

Longitudinal Study of Salivary Biomarkers in the Definition of Clinico‐Molecular Progression of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
Longitudinal changes in salivary biomarkers in Parkinson’s disease (PD) from early (T0) to 4‐year follow‐up (T1), quantified by ELISA: oligomeric and total α‐synuclein, total and phosphorylated tau, MAP1LC3B (autophagy), and TNFa (inflammation). Blue arrows indicate direction of change at T1 vs T0 (up = increase; down = decrease).
Maria Ilenia De Bartolo, Daniele Belvisi, Matteo Costanzo, Claudia Caturano, Francesco Emanuele Bellomi, Carolina Cutrona, Flavia Aiello, Giorgio Leodori, Massimo Marano, Romina Mancinelli, Antonella Conte, Giovanni Fabbrini, Alfredo Berardelli, Giorgio Vivacqua   +13 more
wiley   +1 more source

Immunoglobulin free light chains and interleukin-6 levels in prediction of kidney injury in patients with multiple myeloma

, 2019
Izeta Aganovic-Musinovic, Nesina Avdagić, Nermina Babic, Asja Zaciragic, Orhan Lepara, Jasminko Huskić, Maida Todic-Rakanovic, Izeta Aganovic-Musinovic, Nesina Avdagić, Nermina Babic, Asja Zaciragic, Orhan Lepara, Jasminko Huskić, Maida Todic-Rakanovic   +13 more
openalex   +1 more source

Neurofilament Light Chain in Blood and CSF as Marker of Disease Progression in Mouse Models and in Neurodegenerative Diseases [PDF]

, 2016
Mehtap Bacioglu, Luis F. Maia, Oliver Preische, Juliane Schelle, Anja Apel, Stephan A. Kaeser, Manuel Schweighauser, Timo Eninger, Marius Lambert, Andrea Pilotto, Derya R. Shimshek, Ulf Neumann, Philipp J. Kahle, Matthias Staufenbiel, Manuela Neumann, Walter Maetzler, Jens Kuhle, Mathias Jucker   +17 more
openalex   +1 more source

Metabolomics detects clinically silent neuroinflammatory lesions earlier than neurofilament-light chain in a focal multiple sclerosis animal model [PDF]

, 2022
Tianrong Yeo, Halwan Bayuangga, Marcus Augusto-Oliveira, Megan Sealey, Timothy D. W. Claridge, Rachel Tanner, David Leppert, Jacqueline Palace, Jens Kuhle, Fay Probert, Daniel C Anthony, Tianrong Yeo, Halwan Bayuangga, Marcus Augusto-Oliveira, Megan Sealey, Timothy D. W. Claridge, Rachel Tanner, David Leppert, Jacqueline Palace, Jens Kuhle, Fay Probert, Daniel C Anthony   +21 more
openalex   +1 more source

Single‐Cell RNA Seq in Sydenham Chorea Shows B Cell HLA‐DR/DQ Upregulation and Plasma Cell Proteasomal Activation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The pathogenesis of Sydenham chorea remains unclear. We report a 10‐year‐old girl presenting with subacute chorea and mild carditis following Streptococcal throat infection. Single‐cell RNA sequencing on 30,794 peripheral immune cells from the patient and two sex‐matched controls revealed nine immune cell clusters.
Velda X. Han, Brooke A. Keating, Brian S. Gloss, Xianzhong Lau, Ruwani Dissanayake, Hiroya Nishida, Jessica Hayes, Shrujna Patel, Shekeeb S. Mohammad, Russell C. Dale   +9 more
wiley   +1 more source

Reconstituted Human Myosin Light Chain Phosphatase Reveals Distinct Roles of Two Inhibitory Phosphorylation Sites of the Regulatory Subunit, MYPT1 [PDF]

, 2014
Mukta D. Khasnis, Akiko Nakatomi, Kristyn Gumpper, Masumi Eto   +3 more
openalex   +1 more source