Results 71 to 80 of about 2,711,435 (306)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice [PDF]

, 1994
We have examined the regulatory role of the individual components of the immunoglobulin antigen receptor in B-cell development by transgenic complementation of Rag-1 deficient (Rag-1⁻) mice. Complementation with a membrane µ heavy chain (µHC) gene allows
Baltimore, David, Corcoran, Lynn M., Hardy, Richard R., Nemazee, David, Nussenzweig, Michel C., Roman, Christopher A. J., Schlissel, Mark S., Shinton, Susan A., Silver, Daniel P., Spanopoulou, Eugenia   +9 more
core  

Strong electron-photon coupling in one-dimensional quantum dot chain: Rabi waves and Rabi wavepackets [PDF]

, 2009
We predict and theoretically investigate the new coherent effect of nonlinear quantum optics -- spatial propagation of Rabi oscillations (Rabi waves) in one-dimensional quantum dot (QD) chain.
A. Hoffmann, A. Kavokin, C. Cohen-Tannoudji, E. M. Lifshitz, F. G. Bass, G. Ya. Slepyan, L. Allen, L. Novotny, M. O. Scully, Ph. A. Martin, R. Loudon, S. M. Dutra, Y. D. Yerchak, Y. R. Shen   +13 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Notch signaling in cancer: metabolic reprogramming and therapeutic implications

Frontiers in Immunology
The evolutionarily conserved Notch signaling pathway is essential for cell-fate determination, organogenesis, and tissue homeostasis. Notch receptors and their ligands are transmembrane proteins with epidermal growth factor–like repeats; ligand–receptor ...
Shuang-Shuang Wang, Shuang-Shuang Wang, Shuang-Shuang Wang, Hui-Lin Lv, Hui-Lin Lv, Hui-Lin Lv, Rong-Zu Nie, Rong-Zu Nie, Rong-Zu Nie, Ya-Ping Liu, Ya-Ping Liu, Ya-Ping Liu, Yan-Jie Hou, Yan-Jie Hou, Yan-Jie Hou, Chen Chen, Chen Chen, Chen Chen, Xing-Yue Tao, Xing-Yue Tao, Xing-Yue Tao, Huo-Min Luo, Huo-Min Luo, Huo-Min Luo, Pei-Feng Li, Pei-Feng Li, Pei-Feng Li   +26 more
doaj   +1 more source

Higher-Order Hydrodynamics in 1D: a Promising Direction and a Null Result

, 2017
We derive a Moyal dynamical equation that describes exact time evolution in generic (inhomogeneous) noninteracting spin-chain models. Assuming quasistationarity, we develop a hydrodynamic theory.
Fagotti, Maurizio
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

High-intensity ultrasound of chicken myofibrillar protein under reduced-salt conditions: effect on emulsifying and interfacial properties

Food Science of Animal Products
In this study, the effects of high-intensity ultrasound (HIU, frequency 20 kHz, amplitude 60%, power 450 W) for 0, 6, and 9 min on the emulsifying properties of chicken myofibrillar protein (MP) under different NaCl concentrations (0.2, 0.3, 0.4, and 0.5
Linmeng Wang, Yanfang Zhou, Qing Yang, Lei Fu, Ke Li, Yanhong Bai   +5 more
doaj   +1 more source

Fast and slow light in zig-zag microring resonator chains

, 2008
We analyze fast and slow light transmission in a zig-zag microring resonator chain. This novel device permits the operation in both regimes. In the superluminal case, a new ubiquitous light transmission effect is found whereby the input optical pulse is ...
Blair, Boyd, Boyd, F. J. Fraile-Pelaez, Fraile-Pelaez, Heebner, Khurgin, Khurgin, Liu, Morichetti, P. Chamorro-Posada, Parra, Scheuer, Uranus, Xia, Zirngibl   +15 more
core   +1 more source