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Amyloid Formation in Light Chain Amyloidosis
Current Topics in Medicinal Chemistry, 2013Light chain amyloidosis is one of the unique examples within amyloid diseases where the amyloidogenic precursor is a protein that escapes the quality control machinery and is secreted from the cells to be circulated in the bloodstream. The immunoglobulin light chains are produced by an abnormally proliferative monoclonal population of plasma cells that
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[Amyloid light chain amyloidosis].
Brain and nerve = Shinkei kenkyu no shinpo, 2014Primary amyloid light chain (AL) amyloidosis is the most common and most aggressive form of systemic amyloidosis. In AL amyloidosis, the products of free light chains (FLCs) of monoclonal amyloidogenic plasma cells deposit in the heart, kidneys, liver, gastrointestinal tract, autonomic nerve systems, and soft tissues, consequently leading to ...
Kenshi, Suzuki, Toshiko, Shimizu
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Immunoglobulin Light Chain and Systemic Light-Chain Amyloidosis
2007Light-chain amyloidosis (AL) is characterized by the clonal expansion of plasma B cells that secrete large amounts of monoclonal immunoglobulin light chains. The free light chains circulate in serum and form amyloid fibrils on vital organs such as the kidney, heart, and liver causing organ failure and eventually death.
Marina Ramirez-Alvarado +5 more
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Planning for post‐pandemic cancer care delivery: Recovery or opportunity for redesign?
Ca-A Cancer Journal for Clinicians, 2021Pelin Cinar +2 more
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A roadmap for the commercialization of perovskite light emitters
Nature Reviews Materials, 2022, Richard Friend, Edward H Sargent
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Visible Light-Driven Radical-Mediated C–C Bond Cleavage/Functionalization in Organic Synthesis
Chemical Reviews, 2021Jia-Rong Chen, Wen-Jing Xiao
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Understanding biology to tackle the disease: Multiple myeloma from bench to bedside, and back
Ca-A Cancer Journal for Clinicians, 2014Giada Bianchi
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Photothermal Nanomaterials: A Powerful Light-to-Heat Converter
Chemical Reviews, 2023Ximin Cui, Qifeng Ruan, Xiaolu Zhuo
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MicroRNAome genome: A treasure for cancer diagnosis and therapy
Ca-A Cancer Journal for Clinicians, 2014Ioana Berindan-Neagoe +2 more
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