Results 31 to 40 of about 36,737 (275)

Localized Immunoglobulin Light-Chain Amyloidosis of the Ulnar Nerve

Case Reports in Neurology, 2021
Amyloidosis is a disorder caused by extracellular tissue deposition of insoluble fibrils. Amyloidosis can be divided into systemic or localized disease. Primary systemic amyloidosis is a multisystem disease caused by the deposition of amyloid in various ...
Shinsuke Morisaki, Shinji Tsuchida, Eiichi Konishi, Nagaaki Katoh, Yusuke Takahashi, Kenji Takahashi   +5 more
doaj   +1 more source

Three-dimensional structure of an immunoglobulin light-chain dimer with amyloidogenic properties [PDF]

, 2002
The X-ray structure of an immunoglobulin light-chain dimer isolated from the urine as a 'Bence-Jones protein' from a patient with multiple myeloma and amyloidosis (Sea) was determined at 1.94 Angstrom resolution and refined to R and R-free factors of 0 ...
Bourne, P. C., DeWitt, C. R., Edmundson, A. B., Fan, Z. C., Guddat, L. W., Moomaw, C. R., Ramsland, P. A., Shan, L., Shultz, B. B., Slaughter, C. A., Terzyan, S. S.   +10 more
core   +2 more sources

Breast amyloidosis: a case report [PDF]

, 2016
Amyloidosis is an uncommon disorder characterized by extracellular deposition of abnormal proteins. Breast involvement has rarely been reported and can clinically be misdiagnosed as breast cancer.
Boscaini, Giulia, DE SANTIS, Giorgio, Pignatti, Marco, Tazzioli, Giovanni   +3 more
core   +1 more source

Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient

Nature Communications, 2019
Immunoglobulin Light Chain Amyloidosis (AL) is the most common systemic amyloidosis occurring in Western countries. Here the authors present the 4.0 Å cryo-EM structure of light chain AL55 fibrils that were isolated from the heart of an AL systemic ...
Paolo Swuec, Francesca Lavatelli, Masayoshi Tasaki, Cristina Paissoni, Paola Rognoni, Martina Maritan, Francesca Brambilla, Paolo Milani, Pierluigi Mauri, Carlo Camilloni, Giovanni Palladini, Giampaolo Merlini, Stefano Ricagno, Martino Bolognesi   +13 more
doaj   +1 more source

A common beta-sheet architecture underlies in vitro and in vivo beta(2)-microglobulin amyloid fibrils [PDF]

, 2008
Misfolding and aggregation of normally soluble proteins into amyloid fibrils and their deposition and accumulation underlies a variety of clinically significant diseases.
Jahn, T.R., Radford, S.E., Tennent, G.A.
core   +2 more sources

Idiopathic membranous nephropathy with renal amyloidosis: A case report

Frontiers in Medicine, 2022
BackgroundImmunoglobulin light chain amyloidosis is a clonal, non-proliferative plasma cell disorder, in which fragments of immunoglobulin light chain are deposited in tissues.
Yue Wang, Xueyao Wang, Jinyu Yu, Shan Wu, Zhonggao Xu, Weixia Sun   +5 more
doaj   +1 more source

Incidence and survival in non-hereditary amyloidosis in Sweden [PDF]

, 2012
BACKGROUND: Amyloidosis is a heterogeneous disease caused by deposition of amyloid fibrils in organs and thereby interfering with physiological functions.
Asta Försti, Jan Sundquist, Kari Hemminki, Kristina Sundquist, Xinjun Li   +4 more
core   +1 more source

Dataset on the use of 3D speckle tracking echocardiography in light-chain amyloidosis [PDF]

, 2018
The dataset presented in this article is related to the research article entitled “Biventricular assessment of light-chain amyloidosis using 3D speckle tracking echocardiography: Differentiation from other forms of myocardial hypertrophy” (Vitarelli et ...
Antonio Vitarelli, Carlo Gaudio, Enrico Mangieri, Federico Vozella, Giovanni Truscelli, Lidia Capotosto, Maria Teresa Petrucci, Mario Sergio Pergolini, Serafino Ricci, Silvia Lai, Simone De Sio   +10 more
core   +2 more sources

Light‐chain amyloid myopathy isolated to skeletal muscles: A case report

Clinical Case Reports, 2020
Isolated amyloidosis, especially of amyloid light‐chain type, is an infrequent disease. Systemic chemotherapy for light‐chain amyloidosis isolated to skeletal muscles plays a key role to reduce clonal plasma cells producing aberrant immunoglobulin.
Toshihiro Matsukawa, Katsuki Eguchi, Ichizo Nishino, Kohei Okada, Kazuo Oshimi, Takuto Miyagishima   +5 more
doaj   +1 more source

Light-Chain Amyloidosis: The Great Impostor

Life, 2023
Light-chain amyloidosis (AL) is a disease of protean manifestations due to a wide spectrum of organs that can be affected. The disorder is caused by the deposition of an extracellular amorphous material, the amyloid, which is produced by malignant plasma cells.
Georgia Stefani, Evangelia Kouvata, George Vassilopoulos   +2 more
openaire   +3 more sources