Results 101 to 110 of about 665,153 (306)

Relationship between Speed and Lateral Position on Curves, September 2012

, 2012
Excessive speed is often cited as a primary driver factor in crashes, particularly rural two-lane crashes. It has also been suggested that speed plays a significant role in crashes on curves. However, the relationship between speed and crashes on curves

core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A Application of WD Model to EB Type Contact Binary System [PDF]

Journal of Astronomy and Space Sciences, 2000
The EB type contact binaries show large temperature difference ( T 1,000K) between two components. Thus we have modified the mode 3 of the WD program to adjust albedos, limb darkening coefficients and gravity darkening exponents for both components of ...
Su-Yeon Oh, Kyu-Dong Oh
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Hydrogen-poor Superluminous Supernovae with Bumpy Light Curves Powered by Precessing Magnetars

The Astrophysical Journal
Recent observations and statistical studies have revealed that a significant fraction of hydrogen-poor superluminous supernovae (SLSNe-I) exhibit light curves that deviate from the smooth evolution predicted by the magnetar-powered model, instead showing
Biao Zhang, Long Li, Zi-Gao Dai, Shu-Qing Zhong   +3 more
doaj   +1 more source

Photoelectric Observations and Analysis of the Contact Binary W UMa [PDF]

Journal of Astronomy and Space Sciences, 2001
The unpublished photoelectric observations of the contact binary W UMa in ultraviolet, blue, and yellow bandpasses made on four nights during the observing seasons from April, 1984 to May, 1985 were presented.
Chun-Hwey Kim, Chung Uk Lee, Young Woon Kang   +2 more
doaj  

Classification of Low Earth Orbit (LEO) Resident Space Objects' (RSO) Light Curves Using a Support Vector Machine (SVM) and Long Short-Term Memory (LSTM). [PDF]

Sensors (Basel), 2023
Qashoa R, Lee R.
europepmc   +1 more source

Predicting Variable Star Light Curves [PDF]

International Astronomical Union Colloquium, 1993
AbstractI present a new method to test determinism, in particular the nonlinear behavior, in observed time series of pulsating stars, based on a recent prediction method which exploits the dynamical system theory. A method for filling gaps in data has thereby been constructed.
openaire   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

BLADE: An Automated Framework for Classifying Light Curves from the Center for Near-Earth Object Studies Fireball Database

The Astronomical Journal
Fireballs (bolides) are high-energy luminous phenomena produced when meteoroids and small asteroids enter Earth’s atmosphere at hypersonic speeds, often resulting in fragmentation or complete disintegration accompanied by significant energy release.
Elizabeth A. Silber, Vedant Sawal
doaj   +1 more source