Results 101 to 110 of about 1,818,684 (284)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Hydrogen-poor Superluminous Supernovae with Bumpy Light Curves Powered by Precessing Magnetars

open access: yesThe Astrophysical Journal
Recent observations and statistical studies have revealed that a significant fraction of hydrogen-poor superluminous supernovae (SLSNe-I) exhibit light curves that deviate from the smooth evolution predicted by the magnetar-powered model, instead showing
Biao Zhang   +3 more
doaj   +1 more source

Photoelectric Observations and Analysis of the Contact Binary W UMa [PDF]

open access: yesJournal of Astronomy and Space Sciences, 2001
The unpublished photoelectric observations of the contact binary W UMa in ultraviolet, blue, and yellow bandpasses made on four nights during the observing seasons from April, 1984 to May, 1985 were presented.
Chun-Hwey Kim   +2 more
doaj  

Light curves analysis of AB Andromedae

open access: yesAstronomische Nachrichten, 1986
AbstractThe new B and V light curves of the eclipsing variable AB And obtained during 1979 are analysed. Frequency Domain techniques is used and new geometric and photometric elements are given.
ROVITHISLIVANIOU, H, ROVITHIS, P
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

BLADE: An Automated Framework for Classifying Light Curves from the Center for Near-Earth Object Studies Fireball Database

open access: yesThe Astronomical Journal
Fireballs (bolides) are high-energy luminous phenomena produced when meteoroids and small asteroids enter Earth’s atmosphere at hypersonic speeds, often resulting in fragmentation or complete disintegration accompanied by significant energy release.
Elizabeth A. Silber, Vedant Sawal
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Photometric and Radial Velocity Curves Analyses of the Triple System τ Tauri [PDF]

open access: yesJournal of Astronomy and Space Sciences, 1995
New UBVRI observations of triple star τ Tau were at Chungbuk National University Observatory for 31 nights from Dec. 1990 to Jan. 1994. A total of 2930 photometric observations were obtained with 586 points for each filters, and BVRI light curves were ...
Yong-Sam Lee, Su-Jin Kwon
doaj  

Home - About - Disclaimer - Privacy