Results 81 to 90 of about 636,094 (261)

Light curves and colours of the ejecta from Dimorphos after the DART impact. [PDF]

Nature, 2023
Graykowski A, Lambert RA, Marchis F, Cazeneuve D, Dalba PA, Esposito TM, O'Conner Peluso D, Sgro LA, Blaclard G, Borot A, Malvache A, Marfisi L, Powell TM, Huet P, Limagne M, Payet B, Clarke C, Murabana S, Owen DC, Wasilwa R, Fukui K, Goto T, Guillet B, Huth P, Ishiyama S, Kukita R, Mitchell M, Primm M, Randolph J, Rivett DA, Ryno M, Shimizu M, Toullec JP, Will S, Yue WC, Camilleri M, Graykowski K, Janetzke R, Janke D, Kardel S, Loose M, Pickering JW, Smith BA, Transom IM.   +43 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

EXOSAT X-ray Light Curves of SS ARI [PDF]

Journal of Astronomy and Space Sciences, 1998
We construct the X-ray light curves of the W UMa type contact binary SS Arietis (HD12929) from the EXOSAT data in HEASARC data archive. The phase dependent X-ray light curves obtained by using the ephemeris of Kaluzny & Pojmanski (1984) have been ...
Yonggi Kim
doaj  

The Light Curve Epochs of Supernovae Explosions [PDF]

International Astronomical Union Colloquium, 1980
AbstractA brief description of the current state of knowledge for Type II light curves is given, including discussion of some of the remaining problems. The use of supernovae of both types as independent distance indicators is outlined and difficulties are pointed out. A summary of new ideas regarding the origin of Type I light curves is presented.
openaire   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Classification of Low Earth Orbit (LEO) Resident Space Objects' (RSO) Light Curves Using a Support Vector Machine (SVM) and Long Short-Term Memory (LSTM). [PDF]

Sensors (Basel), 2023
Qashoa R, Lee R.
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Hundreds of TESS Exoplanets Might Be Larger than We Thought

The Astrophysical Journal Letters
The radius of a planet is a fundamental parameter that probes its composition and habitability. Precise radius measurements are typically derived from the fraction of starlight blocked when a planet transits its host star.
Te Han, Paul Robertson, Timothy D. Brandt, Shubham Kanodia, Caleb Cañas, Avi Shporer, George Ricker, Corey Beard   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A Application of WD Model to EB Type Contact Binary System [PDF]

Journal of Astronomy and Space Sciences, 2000
The EB type contact binaries show large temperature difference ( T 1,000K) between two components. Thus we have modified the mode 3 of the WD program to adjust albedos, limb darkening coefficients and gravity darkening exponents for both components of ...
Su-Yeon Oh, Kyu-Dong Oh
doaj