Results 71 to 80 of about 636,094 (261)

Atypical Light Curves

open access: yes, 2013
Presented at the "40 Years of Variable Stars: A Celebration of Contributions by Horace A. Smith" conference (arXiv:1310.0149).
Molnar, Lawrence   +2 more
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

STUDY OF BRIGHTNESS VARIATIONS OF IRAS 07080+0605 FROM THE ASAS SN DATA

open access: yesEurasian Physical Technical Journal
This paper presents the findings of an analysis of the light curve of the star IRAS07080+0605, a member of the FS CMa class. The analysis was conducted using data from the ASAS-SN survey, collected between 2014 and 2025. The year-by-year analysis of the
A.A. Khokhlov   +3 more
doaj   +1 more source

BRIEF COMMUNICATIONPhotosynthetic light-response curves of light-demanding and shade-tolerant seedlings of neotropical tree species

open access: yesPhotosynthetica, 2019
Light-response curves of seedlings of five light-demanding (LD) and four shade-tolerant (ST) neotropical tree species, native to the Brazilian Atlantic biome, were analyzed, aiming to verify differences between these functional groups regarding the light
A.K. CALZAVARA   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Predicting Variable Star Light Curves [PDF]

open access: yesInternational Astronomical Union Colloquium, 1993
AbstractI present a new method to test determinism, in particular the nonlinear behavior, in observed time series of pulsating stars, based on a recent prediction method which exploits the dynamical system theory. A method for filling gaps in data has thereby been constructed.
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

LONG-TERM ACTIVITY CHANGES OF UV PISOIUM

open access: yesOdessa Astronomical Publications, 2017
UV Psc has been observed since 1976 at the Ankara and Ege University Observatories. Mean light curves in B and V colours obtained using the maxima levels of observed light curves of the system.
V. Keskin   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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