Results 91 to 100 of about 665,153 (306)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Characterizing bright δ Scuti pulsators using TESS light curves

We present a study of bright, young δ Scuti stars near the zero-age main sequence using TESS light curves and Gaia DR3 data. From a sample of 2041 stars with G < 7 and GBP − GRP colour in the range 0–0.6, we identified 444 δ Scuti pulsators.
Mani, Prasad, Murphy, Simon J., Bedding, Timothy R., Bernizzoni, Mara, Hey, Daniel   +4 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

EXOSAT X-ray Light Curves of SS ARI [PDF]

Journal of Astronomy and Space Sciences, 1998
We construct the X-ray light curves of the W UMa type contact binary SS Arietis (HD12929) from the EXOSAT data in HEASARC data archive. The phase dependent X-ray light curves obtained by using the ephemeris of Kaluzny & Pojmanski (1984) have been ...
Yonggi Kim
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Atlas of secular light curves of comets [PDF]

Planetary and Space Science, 2010
In this work we have compiled 37,692 observations of 27 periodic and non-periodic comets to create the secular light curves (SLCs), using 2 plots per comet. The data has been reduced homogeneously. Our overriding goal is to learn the properties of the ensemble of comets.
openaire   +2 more sources

Searching for transits in the Wide Field Camera Transit Survey with difference-imaging light curves

, 2013
The Wide Field Camera Transit Survey is a pioneer program aiming at for searching extra-solar planets in the near-infrared. The images from the survey are processed by a data reduction pipeline, which uses aperture photometry to construct the light ...
Carlos del Burgo Díaz
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Hundreds of TESS Exoplanets Might Be Larger than We Thought

The Astrophysical Journal Letters
The radius of a planet is a fundamental parameter that probes its composition and habitability. Precise radius measurements are typically derived from the fraction of starlight blocked when a planet transits its host star.
Te Han, Paul Robertson, Timothy D. Brandt, Shubham Kanodia, Caleb Cañas, Avi Shporer, George Ricker, Corey Beard   +7 more
doaj   +1 more source

Light curves and colours of the ejecta from Dimorphos after the DART impact. [PDF]

Nature, 2023
Graykowski A, Lambert RA, Marchis F, Cazeneuve D, Dalba PA, Esposito TM, O'Conner Peluso D, Sgro LA, Blaclard G, Borot A, Malvache A, Marfisi L, Powell TM, Huet P, Limagne M, Payet B, Clarke C, Murabana S, Owen DC, Wasilwa R, Fukui K, Goto T, Guillet B, Huth P, Ishiyama S, Kukita R, Mitchell M, Primm M, Randolph J, Rivett DA, Ryno M, Shimizu M, Toullec JP, Will S, Yue WC, Camilleri M, Graykowski K, Janetzke R, Janke D, Kardel S, Loose M, Pickering JW, Smith BA, Transom IM.   +43 more
europepmc   +1 more source