Results 111 to 120 of about 4,751,007 (301)

Photometric Light Curves for near-Earth Asteroid 159402 (1999 AP10)

open access: yes, 2022
Light curves for near-Earth asteroid 159402 (1999 AP10) from Physics Innovations Robotic Telescope Explorer (PIRATE) photometric observations.
Benjamin Rozitis (8533006)   +6 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

EXOSAT X-ray Light Curves of SS ARI [PDF]

open access: yesJournal of Astronomy and Space Sciences, 1998
We construct the X-ray light curves of the W UMa type contact binary SS Arietis (HD12929) from the EXOSAT data in HEASARC data archive. The phase dependent X-ray light curves obtained by using the ephemeris of Kaluzny & Pojmanski (1984) have been ...
Yonggi Kim
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Theoretical light curves of type Ia supernovae

open access: yes, 2011
Aims. We present the first theoretical SN Ia light curves calculated with the time-dependent version of the general purpose model atmosphere code PHOENIX. Our goal is to produce light curves and spectra of hydro models of all types of supernovae.
E. Baron, D. Jack, P. H. Hauschildt
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Hydrogen-poor Superluminous Supernovae with Bumpy Light Curves Powered by Precessing Magnetars

open access: yesThe Astrophysical Journal
Recent observations and statistical studies have revealed that a significant fraction of hydrogen-poor superluminous supernovae (SLSNe-I) exhibit light curves that deviate from the smooth evolution predicted by the magnetar-powered model, instead showing
Biao Zhang   +3 more
doaj   +1 more source

octans: Observed calculated diagram and light curves

open access: yes
<p>octans is a Python library designed for easy and robust calculation of light curve extrema timings and the construction of O-C diagrams. It also provides access to various databases to retrieve light curves and extrema times.
Niaei, M., Basturk, O.
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Hundreds of TESS Exoplanets Might Be Larger than We Thought

open access: yesThe Astrophysical Journal Letters
The radius of a planet is a fundamental parameter that probes its composition and habitability. Precise radius measurements are typically derived from the fraction of starlight blocked when a planet transits its host star.
Te Han   +7 more
doaj   +1 more source

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