Results 111 to 120 of about 1,819,617 (345)

Generating artificial light curves: Revisited and updated

, 2013
The production of artificial light curves with known statistical and variability properties is of great importance in astrophysics. Consolidating the confidence levels during cross-correlation studies, understanding the artefacts induced by sampling ...
Emmanoulopoulos, D., McHardy, I. M., Papadakis, I. E.   +2 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

A Late-Time Flattening of Afterglow Light Curves

, 2003
We present a sample of radio afterglow light curves with measured decay slopes which show evidence for a flattening at late times compared to optical and X-ray decay indices.
B. D. Metzger, Bhattacharya D., D. A. Frail, E. Berger, S. A. Yost, S. R. Kulkarni, Sagar R., Wijers R. A. M. J.   +7 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Physics-driven Explosions of Stripped High-mass Stars: Synthetic Light Curves and Spectra of Stripped-envelope Supernovae with Broad Light Curves

The Astrophysical Journal
Stripped-envelope supernovae (SESNe) represent a significant fraction of core-collapse supernovae, arising from massive stars that have shed their hydrogen and, in some cases, helium envelopes. The origins and explosion mechanisms of SESNe remain a topic
Jing Lu, Brandon L. Barker, Jared Goldberg, Wolfgang E. Kerzendorf, Maryam Modjaz, Sean M. Couch, Joshua V. Shields, Andrew G. Fullard   +7 more
doaj   +1 more source

Photometric and Radial Velocity Curves Analyses of the Triple System τ Tauri [PDF]

Journal of Astronomy and Space Sciences, 1995
New UBVRI observations of triple star τ Tau were at Chungbuk National University Observatory for 31 nights from Dec. 1990 to Jan. 1994. A total of 2930 photometric observations were obtained with 586 points for each filters, and BVRI light curves were ...
Yong-Sam Lee, Su-Jin Kwon
doaj  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Ultraviolet Light Curves of Supernovae with Swift Uvot

, 2008
We present ultravioliet (UV) observations of supernovae (SNe) obtained with the UltraViolet/Optical Telescope (UVOT) on board the Swift spacecraft. This is the largest sample of UV light curves from any single instrument and covers all major SN types and
Brown, Brown, Brown, Brown, Bufano, Cappellaro, Contardo, Daniel Vanden Berk, Dessart, Ellis, Folatelli, Foley, Fransson, Fransson, Gal-Yam, Garg, Gehrels, Gezari, Ghisellini, Holland, Immler, Immler, Immler, Immler, Immler, John Nousek, Johnson, Kasliwal, Kuznetsova, Lentz, Lyubimkov, Martin Still, Miller, Milne, Modjaz, Modjaz, Neil Gehrels, Nino Panagia, Nugent, Pagano, Panagia, Panagia, Peter J. Brown, Peter Milne, Peter W. A. Roming, Poole, Poznanski, Pskovskii, Riess, Sako, Stefan Immler, Stephen T. Holland, Stritzinger, Stritzinger, Sullivan, Vanden Berk, Wang, Wang, Wang, Waxman   +59 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Looking for Stars and Finding the Moon: Effects of Lunar Gamma-ray\n Emission on Fermi LAT Light Curves [PDF]

, 2013
R. H. D. Corbet, C. C. Cheung, M. Kerr, Paul S. Ray   +3 more
openalex   +1 more source