Results 61 to 70 of about 1,240,084 (305)

Amplitude reduction and phase shifts of melatonin, cortisol and other circadian rhythms after a gradual advance of sleep and light exposure in humans.

PLoS ONE, 2012
BackgroundThe phase and amplitude of rhythms in physiology and behavior are generated by circadian oscillators and entrained to the 24-h day by exposure to the light-dark cycle and feedback from the sleep-wake cycle.
Derk-Jan Dijk, Jeanne F Duffy, Edward J Silva, Theresa L Shanahan, Diane B Boivin, Charles A Czeisler   +5 more
doaj   +1 more source

Frustrated Tunnel Ionization with Few-cycle Pulses

, 2018
Frustrated tunnel ionization (FTI) is one of the dominant channels in strong field ionization that results in the excitation of atoms. Recent studies have shown that there is a significant number of FTI events for multi-cycle pulses with the theory ...
P. S. Light, Palmer, AJ, Luiten, A.N., R. T. Sang, Dakka, M.A., D. Chetty, Chetty, D., Glover, RD, Sang, R.T., Light, PS, Light, P.S., A. J. Palmer, Luiten, AN, A. N. Luiten, J. L. Holdsworth, I. V. Litvinyuk, M. A. Dakka, R. D. Glover, B. A. deHarak, Glover, R.D., Litvinyuk, IV, Sang, RT, Dakka, MA, Deharak, B.A., Chetty, D, Litvinyuk, I.V., Holdsworth, J.L., Palmer, A.J., De Harak, BA, Holdsworth, JL   +29 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Life-cycle assessment of light steel frame buildings : A systematic literature review. [PDF]

, 2023
Light Steel Frame structures (LSF) have become one of the main competitors of traditional construction systems. The optimized material use, its lightness, and the timesaving in the construction phase, show the potential of this technology to reduce ...
G. Marrone, M. M. Sesana, M. Imperadori
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Stroboscopic lighting with intensity synchronized to rotation velocity alleviates motion sickness gastrointestinal symptoms and motor disorders in rats

Frontiers in Integrative Neuroscience, 2022
Motion sickness (MS) is caused by mismatch between conflicted motion perception produced by motion challenges and expected “internal model” of integrated motion sensory pattern formed under normal condition in the brain.
Yuqi Mao, Leilei Pan, Wenping Li, Shuifeng Xiao, Ruirui Qi, Long Zhao, Junqin Wang, Yiling Cai   +7 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Effect of Light/Dark Cycle on Photosynthetic Pathway Switching and CO2 Absorption in Two Dendrobium Species

Frontiers in Plant Science, 2019
Many Dendrobium species are both ornamental and medicinal plants in China. Several wild species have been exploited to near extinction, and facility cultivation has become an important way to meet the great market demand.
Yongsan Cheng, Dongxian He, Jie He, Genhua Niu, Rongfu Gao   +4 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source