Results 71 to 80 of about 1,240,084 (305)

An insight into light as a chronobiological therapy in affective disorders [PDF]

open access: yes, 2014
The field of chronobiology has vastly expanded over the past few decades, bringing together research from the fields of circadian rhythms and sleep. The importance of the environmental day–night cycle on our health is becoming increasingly evident as we ...
Lall, Gurprit S.   +10 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

The HY5-PIF regulatory module coordinates light and temperature control of photosynthetic gene transcription [PDF]

open access: yes, 2014
The ability to interpret daily and seasonal alterations in light and temperature signals is essential for plant survival. This is particularly important during seedling establishment when the phytochrome photoreceptors activate photosynthetic pigment ...
Stewart, Kelly L.   +29 more
core   +1 more source

Circularity of consumer electronics within Life Cycle (GAP) Analysis

open access: yes, 2022
Life cycle gap analysis is a specific technique to interpret product LCA results with circular economy principles in order to identify potentials for further improvement.
Lätsch, Corinna   +3 more
core   +2 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Kinetics of the xanthophyll cycle and its role in photoprotective memory and response

open access: yesNature Communications, 2023
Efficiently balancing photochemistry and photoprotection is crucial for survival and productivity of photosynthetic organisms in the rapidly fluctuating light levels found in natural environments. The ability to respond quickly to sudden changes in light
Audrey Short   +6 more
doaj   +1 more source

Human Tau in an Ultradian Light-Dark Cycle [PDF]

open access: yesJournal of Biological Rhythms, 2008
Multiple experimental approaches have been used to assess the free-running period, or “tau,” of humans. One approach has been to study circadian rhythms in free-running blind humans. For example, Sack et al. (1992) measured the plasma melatonin rhythm in 11 free-running blind people and reported an average tau of 24.55 h. In sighted humans, at least
Helen J, Burgess, Charmane I, Eastman
openaire   +2 more sources

A probabilistic model for the high cycle fatigue behaviour of cast aluminium alloys subject to complex loads [PDF]

open access: yes, 2013
Lien vers la version éditeur: http://www.sciencedirect.com/science/article/pii/S0142112312002472This article is dedicated to the high cycle fatigue behaviour of cast hypo-eutectic Al–Si alloys and in particular the AlSi7Cu05Mg03 alloy.
PESSARD, Etienne   +3 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

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