Results 91 to 100 of about 12,142,224 (301)

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

To sonify or not to sonify? Educator perceptions of auditory display in interactive simulations

open access: yes, 2021
Presented at the 26th International Conference on Auditory Display (ICAD 2021) 25-28 June 2021, Virtual conference.Presented at the 26th International Conference on Auditory Display (ICAD 2021) 25-28 June 2021, Virtual conference.With the growing ...
Walker, Bruce N.   +2 more
core   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Auditory display and sonification of textured image

open access: yes, 1996
Presented at 3rd International Conference on Auditory Display (ICAD), Palo Alto, California, November 4-6, 1996.Presented at 3rd International Conference on Auditory Display (ICAD), Palo Alto, California, November 4-6, 1996.We propose new methods for ...
Portela, Luis Antonio   +4 more
core   +1 more source

Auditory Display of Coarse Optical Imagery: Concept for a Rehabilitation Aid for Blind Spatial Orientation

open access: yes, 2014
Presented at the 20th International Conference on Auditory Display (ICAD2014), June 22-25, 2014, New York, NY.Presented at the 20th International Conference on Auditory Display (ICAD2014), June 22-25, 2014, New York, NY.We introduce a concept for a ...
Arditi, Aries
core  

Development of portable microfading spectrometers for measurement of light sensitivity of materials [PDF]

open access: yes, 2011
Microfading was originally designed for efficiently detecting extremely light-sensitive materials on objects in situ to determine the appropriate exhibition lighting conditions. By focusing an intense beam of light to a tiny submillimetre sized spot and
Lange, R   +10 more
core  

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

open access: yesFEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli   +2 more
wiley   +1 more source

Analytical model of multiview autostereoscopic 3D display with a barrier or a lenticular plate

open access: yesJournal of Information Display, 2018
A geometric model of an autostereoscopic 3D display is described herein. This model is based on the geometry of typical display devices and on the projective transformations that provide periodicity in the projective space.
Vladimir Saveljev, Irina Palchikova
doaj   +1 more source

A Design Guide-line of Auditory Display for Electric Appliance

open access: yes, 2019
Presented at the 25th International Conference on Auditory Display (ICAD 2019) 23-27 June 2019, Northumbria University, Newcastle upon Tyne, UK.Presented at the 25th International Conference on Auditory Display (ICAD 2019) 23-27 June 2019, Northumbria ...
Komatsu, Takanori   +3 more
core   +1 more source

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