Results 31 to 40 of about 1,735,733 (267)

TeCre: A Novel Temporal Conflict Resolution Method Based on Temporal Knowledge Graph Embedding

Information, 2023
Since the facts in the knowledge graph (KG) cannot be updated automatically over time, some facts have temporal conflicts. To discover and eliminate the temporal conflicts in the KG, this paper proposes a novel temporal conflict resolution method based ...
Jiangtao Ma, Chenyu Zhou, Yonggang Chen, Yanjun Wang, Guangwu Hu, Yaqiong Qiao   +5 more
doaj   +1 more source

The Impact of Tenapanor on Body Composition and Blood Pressure in Peritoneal Dialysis Patients: A Pilot Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida, Kengo Asahina, Keiichi Osano, Natsumi Saegusa, Kohei Yamamura, Kie Ohkoshi, Miho Shikata, Toshihisa Ishii, Makiko Konishi, Kazuya Takahashi, Kohei Uchimura, Ayumu Nakashima   +11 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Extraction of effective elastic constants of perforated plates with triangular hole pattern using modal analysis

Nuclear Engineering and Technology
To extract the effective modulus of elasticity and effective Poisson's ratio, the natural frequencies of fully perforated circular plates with a triangular hole pattern are analyzed using FEA software.
Kyeong-Hoon Jeong, Joo Min Kim, Kwang-Hyun Ahn   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Research Progress on Process Optimization of Metal Materials in Wire Electrical Discharge Machining

Metals
Wire electrical discharge machining (WEDM), as a significant branch of non-traditional machining technologies, is widely applied in fields such as mold manufacturing and aerospace due to its high-precision machining capabilities for hard and complex ...
Xinfeng Zhao, Binghui Dong, Shengwen Dong, Wuyi Ming   +3 more
doaj   +1 more source

Microstructure and Oxidation Behavior of CrAl Laser-Coated Zircaloy-4 Alloy

Metals, 2017
Laser coating of a CrAl layer on Zircaloy-4 alloy was carried out for the surface protection of the Zr substrate at high temperatures, and its microstructural and thermal stability were investigated.
Jeong-Min Kim, Tae-Hyung Ha, Il-Hyun Kim, Hyun-Gil Kim   +3 more
doaj   +1 more source

Rapid revegetation by sowing seed mixtures of shrub and herbaceous species [PDF]

Solid Earth, 2015
Fast revegetation by means of sowing seed mixtures of shrub and herbaceous species is a measure to prevent bare soils from wind and water erosion. A field experiment was used to test the effect of species selection and the ratio of shrub to herbaceous ...
J. Feng, C. Zhang, T. Zhao, Q. Zhang
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source