Results 51 to 60 of about 4,834,015 (307)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Current research status of tumor cell biomarker detection

open access: yesMicrosystems & Nanoengineering, 2023
With the annual increases in the morbidity and mortality rates of tumors, the use of biomarkers for early diagnosis and real-time monitoring of tumor cells is of great importance.
Liying Jiang   +8 more
doaj   +1 more source

Polysaccharide extracted from pomelo fruitlets attenuate hepatic lipid accumulation in hybrid groupers (Epinephelus lanceolatus♂ × Epinephelus fuscoguttatus♀)

open access: yesFrontiers in Marine Science, 2023
IntroductionPomelo is one of the most consumed fruits due to its distinct flavor and sour taste, while large quantities of pomelo fruitlets discard during cultivation and most of them are disposed of as wastes.
Cuiyun Zou   +5 more
doaj   +1 more source

Water on Pt(111): the importance of proton disorder

open access: yes, 2007
The structure of a water adlayer on Pt(111) surface is investigated by extensive first principle calculations. Only allowing for proton disorder the ground state energy can be found. This results from an interplay between water/metal chemical bonding and
Davide Donadio   +6 more
core   +1 more source

Development of semi-theoretical light radiation and photosynthetic growth model for the optimal exploitation of wastewaters by microalgae [PDF]

open access: yes, 2018
In the last decade, interest toward the potential application of microalgae has grown considering their potential use in industrial sectors as human nutrition and health, animal feed and biopolymers. Their ability to use light or/and organic
Bravi, M.   +3 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Visible-Light Photoredox Catalysis in Water

open access: yesThe Journal of Organic Chemistry, 2022
The use of water in organic synthesis draws attention to its green chemistry features and its unique ability to unveil unconventional reactivities. Herein, literature about the use of water as a reaction medium under visible-light photocatalytic conditions is summarized in order to highlight challenges and opportunities.
Camilla Russo   +3 more
openaire   +4 more sources

A physiological investigation of the adaptive significance of juvenility in Pennantia corymbosa Forst : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Botany at Massey University [PDF]

open access: yes, 1978
The responses of the juvenile and adult growth forms of Pennantia corymbosa Forst. to a range of light intensities, leaf temperatures, shoot water potentials and wind velocities were investigated.
Hollows, David Grant
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Spatial and temporal characteristic of PM2.5 and influence factors in the Yellow River Basin

open access: yesFrontiers in Public Health
The Yellow River Basin has been instrumental in advancing ecological preservation and fostering national high-quality development. However, since the advent of China’s reform and opening-up policies, the basin has faced severe environmental pollution ...
Li Han   +4 more
doaj   +1 more source

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