Results 61 to 70 of about 4,834,015 (307)

Edaphic Specialization in Tropical Trees: Physiological Correlates and Responses to Reciprocal Transplantation [PDF]

, 2005
Recent research has documented the importance of edaphic factors in determining the habitat associations of tree species in many tropical rain forests, but the underlying mechanisms for edaphic associations are unclear.
Baltzer, Jennifer L., Burslem, D.F.R.P., Nilus, R., Thomas, Sean C.   +3 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Spatial heterogeneity study of urban expansion and its influencing factors based on multiscale geographically weighted regression – the case of central plains urban agglomeration

Geocarto International
The MGWR model is applied to explore primary drivers of construction land expansion in various land use functional areas. The results show that: (1) owing to differences in economic foundations, functional positioning and development models among various
Jie Wang, Xiaoyan Zhu, Hua Wang, Pengbo Zhao, Mingda Chai, Jiqiang Niu   +5 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Seed Germination in Ginkgo biloba L. I. Influences of Cold Treatment, Gibberellic Acid and Red Light [PDF]

, 1974
The influences of cold treatment, gibberellic acid and red light treatment on rate of germination of seeds of Ginkgo biloba L. were followed for a 12-wk period. Dispersal units were collected, and the outer fleshy layer was removed soon after harvest. Of
Johnson, Michael I., Wickliff, James L.
core   +2 more sources

Sensing a Bacillis anthracis biomarker with well-known OLED emitter EuTta3Phen [PDF]

, 2016
Dipicolinic acid (DPA) is a distinctive biomarker for bacterial spores. Here, we present the successful demonstration of dramatic Switch-OFF sensing of DPA using an easily synthesised Eu(III) phosphor applied primarily in light-emitting devices.
Aspinall, Binnemans, Bünzli, Cable, Cable, Cable, Freund, Georges, Jernigan, Kaltsoyannis, Lee, Liu, Murrel, Sano, Smith, Tan, Thibon, Wang, Zhong   +18 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Application of multi-information integration technology in nondestructive detection of navel orange sugar content

Shipin yu jixie
ObjectiveTo solve the problem of low detection accuracy in existing nondestructive detection methods for navel orange sugar content.MethodsBased on the analysis of detection schemes, a multi-information integration method for nondestructive detection of ...
HE Xiaotian, WANG Wenfan, SHEN Jie, TIAN Erlin   +3 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source