Results 61 to 70 of about 9,821,377 (285)

Water in the 2000 Virginia General Assembly

, 2000
The Virginia General Assembly held its 2000 session from January 12 to March 10. Lawmakers considered 3,172 bills and resolutions (compared to 2,735 measures considered in 1999).
Virginia Water Resources Research Center
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Water in the 2005 Virginia General Assembly

, 2005
The 2005 Virginia General Assembly convened January 12 and adjourned February 27, with a reconvened (“veto”) session on April 6. The legislature considered 3363 measures (2938 introduced this year and 425 carried over from last year); 1610 measures ...
Virginia Water Resources Research Center
core  

Learning neural representations for X-ray ptychography reconstruction with unknown probes

npj Computational Materials
X-ray ptychography provides exceptional nanoscale resolution and is widely applied in materials science, biology, and nanotechnology. However, its full potential is constrained by the critical challenge of accurately reconstructing images when the ...
Tingyou Li, Zixin Xu, Zirui Gao, Hanfei Yan, Xiaojing Huang, Jizhou Li   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Water in the 2010 Virginia General Assembly

, 2010
The 2010 Virginia General Assembly convened January 13 and adjourned March 13. The reconvened (“veto”) session was held April 21. During the session, the Assembly considered 2964 measures, passing 1598 of them, defeating 1093, and continuing 273 until ...
Virginia Water Resources Research Center
core  

Bioconversion of Alpha-Cembratriene-4,6-diol into High-Value Compound Farnesal Through Employment of a Novel Stenotrophomonas maltophilia H3-1 Strain

Molecules
Alpha-cembratriene-4,6-diol (α-CBT-diol) is a complex diterpenoid primarily found in Solanaceae (i.e., tobacco leaves), Pinaceae, and marine corals. Due to its intricate chemical structure, it serves as a precursor for several aroma compounds, including ...
Shen Huang, Jiaming Cheng, Huibo Hu, Aamir Rasool, Robina Manzoor, Duobin Mao   +5 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Water in the 2006 Virginia General Assembly

, 2006
The 2006 Virginia General Assembly convened January 11 and adjourned March 11, with a reconvened (“veto”) session on April 19. The legislature considered 3287 measures; among the most important business was development of the biennial state budget. Below
Virginia Water Resources Research Center
core  

Effect of fly ash content on the performance of hardened cement-based materials suffered from high temperatures

Case Studies in Construction Materials
Fire resistance is an important performance for cement-based materials used in constructions and buildings. In this work, the properties of the hardened cement pastes (HCP) and mortars blended with 0–50% fly ash (FA) suffered from high temperatures were ...
Ying Li, Wenda Xu, Jinbao Zhu, Lin Yang
doaj   +1 more source