Results 131 to 140 of about 59,652 (188)

Dietary anthocyanidin pelargonidin activates G protein‐coupled receptor 35

The FEBS Journal, EarlyView.
Pelargonidin, a red‐fruit‐derived anthocyanidin, was newly identified as a dietary agonist of GPR35, a metabolite‐sensing GPCR implicated in anti‐inflammation. Through screening of dietary compounds, pelargonidin emerged as a potent GPR35 agonist, attenuating inflammation in human intestinal cells.
Fumie Nakashima, Sayako Shimomura, Mayuka Wakabayashi, Wei Qi Loh, Harumi Ando, Haruka Sei, Hiroyuki Hattori, Didik Huswo Utomo, Masaki Kita, Asuka Inoue, Koji Uchida, Takahiro Shibata   +11 more
wiley   +1 more source

Co‐localization of tau and TDP‐43 after extracellular vesicle delivery to cells

The FEBS Journal, EarlyView.
Extracellular vesicles (EVs) derived from donor cells transfected with EGFP–2N4R‐tau or mCherry‐wtTDP‐43 were taken up by recipient cells, leading to cytosolic co‐localization of tau and TDP‐43. Molecular modeling revealed that tau and TDP‐43 directly interact through hydrogen bonding, suggesting a mechanistic link underlying their co‐pathology ...
Farhang Aliakbari, Kathryn Volkening, Zahra Nayeri, Aysegul Yucel Polat, Neil Donison, Jacqueline Palik, Michael J. Strong   +6 more
wiley   +1 more source

Natural disaster risk salience and the strategic appointment of directors with sustainability expertise

Journal of Financial Research, EarlyView.
Abstract This article examines how salient sustainability risks from near‐miss natural disasters influence board composition. Using a difference‐in‐differences design, I find that firms located in counties neighboring disaster‐affected areas significantly increase the presence of directors with sustainability expertise following the disaster.
Bo Wang
wiley   +1 more source

Axial muscle‐fibre orientations in larval zebrafish

Journal of Anatomy, Volume 246, Issue 4, Page 517-533, April 2025.
In 4 days post‐fertilization zebrafish larvae, the fast axial muscle fibres follow helical trajectories that taper towards the tail. Adjacent muscle fibres form substantial angles relative to each other to accommodate this pattern. Using a novel semi‐automatic method, we quantified 3D fibre angles over the whole muscle volume.
Noraly M. M. E. van Meer, Johan L. van Leeuwen, Henk Schipper, Martin J. Lankheet   +3 more
wiley   +1 more source

Glucuronoyl Esterase of Pathogenic Phanerochaete carnosa Induces Immune Responses in Aspen Independently of Its Enzymatic Activity

Plant Biotechnology Journal, EarlyView.
ABSTRACT Microbial enzymes expressed in plants add new functionalities but occasionally trigger undesirable immune responses. Phanerochaete carnosa glucuronoyl esterase (PcGCE) hydrolyses the bond between lignin and 4‐O‐methyl‐α‐D‐glucuronic acid substituent of glucuronoxylan.
Evgeniy N. Donev, Marta Derba‐Maceluch, Xiao‐Kun Liu, Henri Colyn Bwanika, Izabela Dobrowolska, Mohit Thapa, Joanna Leśniewska, Jan Šimura, Alex Yi‐Lin Tsai, Konrad S. Krajewski, Dan Boström, Leszek A. Kleczkowski, Maria E. Eriksson, Karin Ljung, Emma R. Master, Ewa J. Mellerowicz   +15 more
wiley   +1 more source

Cause Identification of Electromagnetic Transient Events using Spatiotemporal Feature Learning

, 2019
This paper presents a spatiotemporal unsupervised feature learning method for cause identification of electromagnetic transient events (EMTE) in power grids.
Arghandeh, Reza, Hamidi, Reza Jalilzadeh, Livani, Hanif, Niazazari, Iman   +3 more
core  

A High‐Throughput Phenotyping Pipeline for Quinoa (Chenopodium quinoa) Panicles Using Image Analysis With Convolutional Neural Networks

Plant Breeding, EarlyView.
ABSTRACT Quinoa is a grain crop with excellent nutritional properties that has attracted global attention for its potential contribution to future food security in a changing climate. Despite its long history of cultivation, quinoa has been improved little by modern breeding and is a niche crop outside its native cultivation area.
Flavio Lozano‐Isla, Lydia Kienbaum, Bettina I. G. Haussmann, Karl Schmid   +3 more
wiley   +1 more source

Laws and Reasons Why

Analytic Philosophy, EarlyView.
ABSTRACT Laws play some role in explanations: at the very least, they somehow connect what is explained, or the explanandum, to what explains, or the explanans. Thus, thermodynamical laws connect the match's being struck and its lightning, so that the former causes the latter; and laws about set formation connect Socrates' existence with {Socrates}'s ...
Julio De Rizzo
wiley   +1 more source

The Distinctness of Objects Near and Far

Philosophy and Phenomenological Research, EarlyView.
ABSTRACT Philosophers working on the metaphysics of persistence typically do not extend their views to the distinctness of objects at a single time. I argue that we can provide criteria to distinguish objects across time if and only if we can provide criteria to distinguish objects at a time. Furthermore, I endorse a stronger claim.
Erica Shumener
wiley   +1 more source

Experimental Study on Lightning Transient Overvoltage Damage of Interface Devices of High-speed Railway Signal Equipment

工程科学与技术
This article proposes a method for detecting and determining the lightning overvoltage damage in communication interfaces of high-speed railway signal equipment, which is an optimization and improvement of the current lightning test and detection methods
Zhoulong WANG, Jinpeng XU, Shaoyun JIN, Ruikun MAI   +3 more
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