Causal Prediction of TP53 Variant Pathogenicity Using a Perturbation‐Informed Protein Language Model
A TP53‐specific predictor, CaVepP53, is developed by fine‐tuning ESMC on experimentally validated variants, quantifying pathogenicity via Euclidean distances. It outperforms general‐purpose models and extends to five cancer genes, enabling interpretable variant classification for precision medicine.
Huiying Chen +15 more
wiley +1 more source
Further observations on the security of Speck32-like ciphers using machine learning. [PDF]
Hou Z, Ren J, Chen S.
europepmc +1 more source
A Perspective on Interactive Theorem Provers in Physics
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley +1 more source
Integrity verified lightweight ciphering for secure medical image sharing between embedded SoCs. [PDF]
Janakiraman S +5 more
europepmc +1 more source
A Bottom‐Up Design Framework for Multifunctional Lattice Metamaterials
This study introduces a generative AI framework for designing multifunctional lattice metamaterials. The method combines 3D Gaussian voxel generation with deep learning, enabling greater design freedom and structural performance. The optimized lattice metamaterials achieve enhanced energy absorption by 40–200% compared to conventional structures and ...
Zongxin Hu +13 more
wiley +1 more source
IAESR: IoT-oriented authenticated encryption based on iShadow round function. [PDF]
Zhang Y +5 more
europepmc +1 more source
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong +7 more
wiley +1 more source
An IoT based remote medical diagnosis system using one time pad cipher over MQTT protocol. [PDF]
Kumar NR +5 more
europepmc +1 more source
Learnable Diffusion Framework for Mouse V1 Neural Decoding
We introduce Sensorium‐Viz, a diffusion‐based framework for reconstructing high‐fidelity visual stimuli from mouse primary visual cortex activity. By integrating a novel spatial embedding module with a Diffusion Transformer (DiT) and a synthetic‐response augmentation strategy, our model outperforms state‐of‐the‐art fMRI‐based baselines, enabling robust
Kaiwen Deng +2 more
wiley +1 more source
Edge-Enabled Hybrid Encryption Framework for Secure Health Information Exchange in IoT-Based Smart Healthcare Systems. [PDF]
Ghani NA +4 more
europepmc +1 more source

