Results 21 to 30 of about 34,077 (277)
Mechanism Underlying the Reversal of Drug Resistance in P-Glycoprotein-Expressing Leukemia Cells by Pinoresinol and the Study of a Derivative [PDF]
P-glycoprotein (P-gp) is a membrane protein associated with multidrug resistance (MDR) due to its key role in mediating the traffic of chemotherapeutic drugs outside cancer cells, leading to a cellular response that hinders efforts toward successful ...
Carpinella, Maria Cecilia +10 more
core +2 more sources
Gene-to-metabolite network for biosynthesis of lignans in MeJA-elicited Isatis indigotica hairy root cultures. [PDF]
Root and leaf tissue of Isatis indigotica shows notable anti-viral efficacy, and are widely used as "Banlangen" and "Daqingye" in traditional Chinese medicine.
Chen, Junfeng +9 more
core +2 more sources
NMR Characterization of Lignans
Lignans are particularly interesting secondary metabolites belonging to the phenyl-propanoid biosynthetic pathway. From the structural point of view, these molecules could belong to the aryltetralin, arylnaphtalene, or dibenzylbutyrolactone molecular skeleton.
Consonni R, Ottolina G
openaire +4 more sources
Collectively, plants contain several different families of natural products among which are compounds with weak estrogenic or antiestrogenic activity toward mammals.
Adlercreutz H +37 more
core +1 more source
Dietary intake and main sources of plant lignans in five European countries
Background: Dietary intakes of plant lignans have been hypothesized to be inversely associated with the risk of developing cardiovascular disease and cancer.
Inge Tetens +10 more
doaj +1 more source
Lignan polyphenols derived from plants are metabolized by bacteria in the gut to mammalian lignans, such as enterolactone (ENL) and enterodiol (END). Mammalian lignan intake has been reported to be associated with obesity and low blood glucose levels ...
Tomoko Fujitani +4 more
doaj +1 more source
Maternal and Paternal Risk Factors for Cryptorchidism and Hypospadias: A Case–Control Study in Newborn Boys [PDF]
Little is known on environmental risk factors for cryptorchidism and hypospadias, which are among the most frequent congenital abnormalities. The aim of our study was to identify risk factors for cryptorchidism and hypospadias, with a focus on potential ...
Alex Burdorf +8 more
core +2 more sources
Sesame (Sesamum indicum L.) is a plant that belongs to the Pedaliaceae family which was first classified as a food source around 4000 years ago. Lignans (sesamin, sesamolin, sesamol, and sesaminol) present in sesame are the primary functional compounds ...
A-Young Kim +3 more
doaj +1 more source
Profiling of oligolignols reveals monolignol coupling conditions in lignifying poplar xylem [PDF]
Lignin is an aromatic heteropolymer, abundantly present in the walls of secondary thickened cells. Although much research has been devoted to the structure and composition of the polymer to obtain insight into lignin polymerization, the low-molecular ...
Boerjan, Wout +7 more
core +3 more sources
Dietary phytoestrogens and esophageal cancer [PDF]
Esophageal cancer is the eighth most common invasive cancer in the world, a cancer with an increasing incidence and male predominance, and there is a great need for potential dietary prevention.
Lin, Yulan
core +1 more source

