Results 141 to 150 of about 737,462 (259)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

The PS4-likelihood ratio calculator: flexible allocation of evidence weighting for case-control data in variant classification. [PDF]

J Med Genet
Rowlands CF, Garrett A, Allen S, Durkie M, Burghel GJ, Robinson R, Callaway A, Field J, Frugtniet B, Palmer-Smith S, Grant J, Pagan J, McDevitt T, McVeigh TP, Hanson H, Whiffin N, Jones M, Turnbull C, CanVIG-UK.   +18 more
europepmc   +1 more source

Likelihood ratios

, 2015
Matt Morgan, Stefan Tigges, Joachim Feger   +2 more
openaire   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Revisiting the speaker discriminatory power of vowel formant frequencies under a likelihood ratio-based paradigm: The case of mismatched speaking styles. [PDF]

PLoS One
Cavalcanti JC, Eriksson A, Barbosa PA, Madureira S.   +3 more
europepmc   +1 more source

A likelihood ratio approach for identifying three-quarter siblings in genetic databases. [PDF]

Heredity (Edinb), 2021
Galván-Femenía I, Barceló-Vidal C, Sumoy L, Moreno V, de Cid R, Graffelman J.   +5 more
europepmc   +1 more source

Likelihood Ratio, positives [PDF]

, 2018
R.-D. Hilgers, N. Heussen, S. Stanzel
openaire   +2 more sources

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

An approach to unified formulae for likelihood ratio calculation in pairwise kinship analysis. [PDF]

Front Genet
Ma G, Wang Q, Cong B, Li S.
europepmc   +1 more source

Pairwise relatedness testing in the context of inbreeding: expectation and variance of the likelihood ratio. [PDF]

Int J Legal Med, 2021
Brustad HK, Vigeland MD, Egeland T.
europepmc   +1 more source