Results 91 to 100 of about 49,716 (300)
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Background Catharanthus roseus Madagascar periwinkle is a well-known medicinal plant that produces a variety of alkaloids with significant pharmacological activities particularly in cancer and diabetes treatment.Aim This study aimed ...
Ramgopal M Dhanwad, Usha R, Ganesh S
doaj +1 more source
Walter Benjamin's theoretical linguistic considerations of the "Doctrine of Likeness" and the project "On the Mimetic Capacity'' were formulated in close—not only close in time—connection with the recording of Berlin Childhood Around Nineteen Hundred ...
Werner Hamacher
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Likeness, Familiarity, and the Ambient Portrait Average
© The Author(s) 2020. This artist-led research project involved 10 visual artists producing 10 ambient portraits and a portrait average of a locally familiar Sitter, and 10 ambient portraits and a portrait average of a less locally familiar Sitter.
Julie Telenta (8688903) +11 more
core
NaPLeS: a natural products likeness scorer—web application and database
Natural products (NPs), often also referred to as secondary metabolites, are small molecules synthesised by living organisms. Natural products are of interest due to their bioactivity and in this context as starting points for the development of drugs ...
Maria Sorokina, Christoph Steinbeck
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Magidor-like and radin-like forcing
Smith College, Northampton, MA 01063, USA Communicated by A. Nerode Received 15 April 1983 We force over a model M of ZF+ K + (K)
openaire +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
An image information sheet, featuring a photograph of Ben and Frances Hooks with a wax likeness of Ben during the annual NAACP ...
core

