Results 101 to 110 of about 49,716 (300)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

BRYAN (J.) Likeness and Likelihood in the Presocratics and Plato

open access: yes, 2014
A review of "Likeness and Likelihood in the Presocratics and Plato"
Rowett, Catherine
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Generalization of Ruspini's Likeness Relation in Cases of Subnormal Relations [PDF]

open access: yes, 1999
The note deals in a preliminary way with the problem of a generalization of a likeness relation. Preliminary results are considered. Defmition of generalized likeness relation is proposed.
Viattchenin, D. A.
core   +1 more source

Quantification of Human-Like Motion of Androids in Relation to Control Parameters

open access: yesIEEE Access
In android science, the greater the resemblance between an android and a human, the greater is the expectation of observers for its movements to appear natural; therefore, the “human-likeness” of android motion is important.
Nihiro Tamura   +3 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

The Beekeeping Sector of Kazakhstan and Contributions to the Pharmaceutical Industry: Promising Flavonoids with the Pharmacokinetic Properties Via the Computational Evaluations [version 1; peer review: 2 approved]

open access: yesF1000Research
Background Bee products are rich sources of bioactive flavonoids with potential applications in nutraceutical and pharmaceutical research. However, differences in the physicochemical and pharmacokinetic properties of individual flavonoids may ...
Şeyda Kaya   +5 more
doaj   +1 more source

A Special Class of Univalent Functions in Hele-Shaw Flow Problems

open access: yesAbstract and Applied Analysis, 2011
We study the time evolution of the free boundary of a viscous fluid for planar flows in Hele-Shaw cells under injection. Applying methods from the theory of univalent functions, we prove the invariance in time of Φ-likeness property (a geometric property
Paula Curt, Denisa Fericean
doaj   +1 more source

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