Guideline for Limb‐Salvage Treatment of Osteosarcoma
Osteosarcoma is the most common primary malignant bone tumor, occurring mainly in children and adolescents, and the limbs are the main affected sites.
Ming Xu +4 more
doaj +2 more sources
Background Historically, amputation was the primary surgical treatment for osteosarcoma of the extremities; however, with advancements in surgical techniques and chemotherapies limb salvage has replaced amputation as the dominant treatment paradigm. This
Daniel R. Evans +6 more
doaj +2 more sources
Advances in limb salvage treatment of osteosarcoma
Osteosarcoma is the most common primary malignant bone tumor; its standard treatment includes neoadjuvant chemotherapy combined with surgery. Neoadjuvant chemotherapy has significantly improved the 5-year survival and limb salvage rates in osteosarcoma ...
Yichun Yang +9 more
doaj +2 more sources
A comparative study between limb-salvage and amputation for treating osteosarcoma
Purpose: Osteosarcoma is an aggressive malignant neoplasm, and conflicting findings have been reported on the survival and function recovery in osteosarcoma patients experiencing limb salvage or amputation.
Xiaojuan Li +12 more
doaj +2 more sources
Outcomes of infrapopliteal angioplasty for limb salvage based on the updated TASC II classification
Purpose:We aimed to evaluate limb salvage, defined as freedom from major amputation, and to identify predictors of major amputation in patients with infrapopliteal peripheral arterial disease (PAD) based on the updated 2015 TASC II anatomic ...
Hong Kuan Kok +5 more
doaj +2 more sources
Primary amputation versus limb salvage in upper limb major trauma: a systematic review
Severe upper limb injuries can result in devastating consequences to functional and psychological well-being. Primary objectives of this review were to evaluate indications for amputation versus limb salvage in upper limb major trauma and whether any ...
S. Nayar, Harry Alcock, D. Edwards
semanticscholar +1 more source
A Comparison of Four-Year Health Outcomes following Combat Amputation and Limb Salvage
Little research has described the long-term health outcomes of patients who had combat-related amputations or leg-threatening injuries. We conducted retrospective analysis of Department of Defense and Department of Veterans Affairs health data for lower ...
Ted Melcer +5 more
openalex +3 more sources
Adamantinoma: A review of the current literature
Adamantinoma is a rare primary low-grade malignant tumour of the appendicular skeleton most commonly found in the tibia. It has an indolent course, with local recurrences and lung metastases occurring over a protracted duration.
Sarah Louise Smyth +4 more
doaj +1 more source
Limb Salvage Versus Amputation: A Review of the Current Evidence
In the trauma situation where the trauma team is faced with a severely injured limb, it requires judicious thinking and evaluating not only the injury in isolation but the patient as a whole when considering the management options.
M. Qureshi +3 more
semanticscholar +1 more source
Fifty tumor necrosis factor-based isolated limb perfusions for limb salvage in patients older than 75 years with limb-threatening soft tissue sarcomas and other extremity tumors [PDF]
BACKGROUND: Isolated limb perfusion (ILP) with tumor necrosis factor (TNF) and melphalan is highly effective in treating limb-threatening soft tissue sarcoma (STS) and other bulky tumors.
Eggermont, A.M.M. (Alexander) +3 more
core +1 more source

