Results 31 to 40 of about 684,067 (406)

Major Limb Amputations: A Tertiary Hospital Experience in Northwestern Tanzania. [PDF]

, 2012
Major limb amputation is reported to be a major but preventable public health problem that is associated with profound economic, social and psychological effects on the patient and family especially in developing countries where the prosthetic services ...
Chalya, Phillipo L, Chandika, Alphonce B, Dass, Ramesh M, Gilyoma, Japhet M, Mabula, Joseph B, Mbelenge, Nkinda, Ngayomela, Isdori H   +6 more
core   +3 more sources

Editor's choice : European Society for Vascular Surgery (ESVS) 2020 clinical practice guidelines on the management of acute limb ischaemia

, 2020
A
Acosta, Stefan, Azuma, Nobuyoshi, Bastos Gonçalves, Frederico, Björck, Martin, Boyle, Jonathan R., Chakfé, Nabil, Choke, Edward T. C., Cochennec, Frederic, Cohnert, Tina U., de Borst, Gert J., Document Reviewers, Earnshaw, Jonothan J., ESVS Guidelines Committee, Fitridge, Robert A., Forbes, Thomas L., Hamady, Mohamad S., Hinchliffe, Robert, Jongkind, Vincent, Kakkos, Stavros K., Koelemay, Mark J. W., Koncar, Igor, Lindholt, Jes S., Mani, Kevin, Menyhei, Gabor, Munoz, Alberto, Müller-Hülsbeck, Stefan, Rai, Kumud, Sebastian Debus, E., Svetlikov, Alexei V., Tshomba, Yamume, Tulamo, Riikka, van den Berg, Jos C., Vega de Ceniga, Melina, Vermassen, Frank   +33 more
core   +2 more sources

Temozolomide combined with irinotecan regresses a cisplatinum-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) precision-oncology mouse model. [PDF]

, 2017
Relapsed osteosarcoma is a recalcitrant tumor. A patient's cisplatinum (CDDP)-resistant relapsed osteosarcoma lung metastasis was previously established orthotopically in the distal femur of mice to establish a patient-derived orthotopic xenograft (PDOX)
Dry, Sarah M., Eckardt, Mark A., Eilber, Fritz C., Elliott, Irmina A., Hayashi, Katsuhiro, Hoffman, Robert M., Igarashi, Kentaro, Kawaguchi, Kei, Kimura, Hiroaki, Kiyuna, Tasuku, Li, Yunfeng, Miwa, Shinji, Miyake, Kentaro, Miyake, Masuyo, Nelson, Scott D., Russell, Tara A., Singh, Arun S., Tsuchiya, Hiroyuki, Yamamoto, Norio, 三輪, 真嗣, 五十嵐, 健太郎, 土屋, 弘行, 山本, 憲男, 林, 克洋   +23 more
core   +1 more source

Amputation Predisposes to Higher Cancer-Specific Mortality Than Limb Salvage Surgery in Pediatric Patients With Osteosarcoma of the Limbs: A Propensity Matching Analysis

Frontiers in Surgery, 2022
ObjectiveWith the development of osteosarcoma treatment, limb salvage surgery is gradually replacing amputation as the primary surgical option. Most pediatric osteosarcomas of the limbs undergo limb-salvage surgery.
Jinkui Wang, Jie Tang, Xiaojun Tan, Chenghao Zhanghuang, Liming Jin, Mujie Li, Zhaoxia Zhang, Tao Mi, Dawei He   +8 more
doaj   +1 more source

Limb-salvage surgery versus extremity amputation for early-stage bone cancer in the extremities: a population-based study

Frontiers in Surgery, 2023
BackgroundMany attempts have been made to induce limb salvage as an alternative to amputation for primary bone cancer in the extremities, but efforts to establish its benefits over amputation yielded inconsistent results with regard to outcomes and ...
Yixu Zhu, Xuesong Wu, Wenjun Zhang, Haijun Zhang   +3 more
doaj   +1 more source

A patient-derived orthotopic xenograft (PDOX) mouse model of a cisplatinum-resistant osteosarcoma lung metastasis that was sensitive to temozolomide and trabectedin: implications for precision oncology. [PDF]

, 2017
In the present study, we evaluated the efficacy of trabectedin (TRAB) and temozolomide (TEM) compared to cisplatinum (CDDP) on a patient-derived orthotopic xenogrraft (PDOX) of a lung-metastasis from an osteosarcoma of a patient who failed CDDP therapy ...
Dry, Sarah M, Eilber, Fritz C, Elliott, Irmina, Hoffman, Robert M, Igarashi, Kentaro, Kawaguchi, Kei, Kiyuna, Tasuku, Li, Yunfeng, Miyake, Kentaro, Murakami, Takashi, Nelson, Scott D, Russell, Tara A, Singh, Arun S, Tsuchiya, Hiroyuki, Yanagawa, Jane, Zhang, Yong   +15 more
core   +1 more source

Use of Flap Salvage for Lower Extremity Chronic Wounds Occurs Most Often in Competitive Hospital Markets

Plastic and Reconstructive Surgery, Global Open, 2021
Background:. Wounds in the comorbid population require limb salvage to prevent amputation. Extensive health economics literature demonstrates that hospital activities are influenced by level of market concentration.
Kenneth L. Fan, MD, Tanvee Singh, MPH, Jenna C. Bekeny, BA, Elizabeth G. Zolper, BS, Paige K. Dekker, BA, Christopher E. Attinger, MD, Karen K. Evans, MD, Derek DeLia, PhD   +7 more
doaj   +1 more source

Limb salvage in the octogenarian

Journal of British Surgery, 1999
Abstract Background Critical limb ischaemia (CLI) presents a unique set of problems in the elderly patient. Foremost among these is the much greater likelihood of loss of independence and reduced quality of life if major amputation is required. For this reason it has been this unit's policy to attempt
A.R. Wilkinson, P Ramamoorthy, Peter T. McCollum, JM Galloway, BJ Johnson   +4 more
openaire   +2 more sources

An extendable modular endoprosthetic system for bone tumour management in the leg [PDF]

, 1990
A modular endoprosthetic system has been developed at the Groningen University Hospital and the University of Twente. The system can bridge a defect resulting from the resection of a malignant bone tumour which has developed around the knee joint of a ...
Grootenboer, H.J., Kroonenberg, H.H. van den, Nielsen, H.K.L., Oldhoff, J., Postma, A., Schraffordt Koops, H., Verkerke, G.J., Veth, R.P.H.   +7 more
core   +6 more sources

Functional and psychological outcomes of delayed lower limb amputation following failed lower limb reconstruction [PDF]

, 2016
The purpose of this study was to evaluate the functional and psychological outcomes of patients who underwent delayed lower limb amputation following failed limb salvage surgery.This retrospective, descriptive study evaluated functional outcomes using ...
Birkholtz, Franz, Hohmann, Erik, Tetsworth, Kevin, van der Merwe, Lana   +3 more
core   +1 more source