Results 61 to 70 of about 24,999 (309)

Civilian popliteal artery injuries : a ten year audit in an urban trauma centre [PDF]

, 2011
The aim of this study is to identify factors associated with limb loss in patients with popliteal artery injuries. Retrospective chart review of a prospectively collected data base of all patients with popliteal artery injuries presenting to the Groote ...
Banderker, Mohammed Asif
core  

Composite sequential arterial reconstruction for limb salvage [PDF]

, 2002
Objective: Autogenous vein is the conduit of choice in patients presenting for infrainguinal arterial reconstruction. Venous conduit may be limited because of inadequacy or prior utilization.
Darling, R.Clement, Mehta, Manish, Roddy, Sean P., Ozsvath, Kathleen J., Kreienberg, Paul B., Mathew, Thomas S., Paty, Philip S.K., Shah, Dhiraj M., Chang, Benjamin B.   +8 more
core   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

Negative-Pressure Wound Therapy in Diabetic Foot Management: Synthesis of International Randomized Evidence over Two Decades

Diabetology
Background: Diabetic foot ulcers (DFUs) carry high risks of infection, amputation, and mortality. We systematically reviewed randomized controlled trials (RCTs) of negative-pressure wound therapy (NPWT), including single-use systems, for clinically ...
George Theodorakopoulos, David G. Armstrong   +1 more
doaj   +1 more source

Outcome of Surgical Treatment of Pelvic Osteosarcoma: Hospital Universiti Sains Malaysia Experience [PDF]

Malaysian Orthopaedic Journal, 2013
We reviewed the surgical treatment and outcomes of 13 patients with pelvic osteosarcoma treated in our centre in the past decade. The study sample included 9 males and 4 females with a mean age of 28.1 years.
MS Ariff, W Zulmi, WI Faisham, MZ Nor Azman, AH Nawaz   +4 more
doaj   +1 more source

THE COST-EFFECTIVENESS OF LIMB SALVAGE FOR BONE TUMOURS [PDF]

, 1997
The use of endoprostheses for limb salvage in primary bone tumours is highly specialised. Studies have shown no significant difference in survival, function or quality of life between patients with limb salvage and those with amputation.
S. R. Carter, R. J. Grimer, P. B. Pynsent   +2 more
core   +1 more source

Reinnervation of Muscle Targets Enhances the Separability of Motor Unit Signals Following Peripheral Nerve Transfers

Advanced Science, EarlyView.
Injured or cut peripheral nerves can be surgically rerouted to reinnervate new muscle targets. This study demonstrates reinnervated muscles exhibit enhanced separability between individual motor unit signals, which can simplify signal recording and decomposition. These findings highlight the potential of reinnervated muscle to serve as a key biological
Kiara N Quinn, Siyu Wang, Lang Qin, Alessandro Ascani Orsini, Kenzi Griffith, Rachana Suresh, Fausto Kang, Pierce L Perkins, Neha Joshi, Alexis L Lowe, Sami Tuffaha, Nitish V Thakor   +11 more
wiley   +1 more source

The First Year of Remission: A Systematic Review and Meta-Analysis of 12-Month Diabetic Foot Ulcer Recurrence

Diabetology
Background: Preventing diabetic foot ulcer (DFU) recurrence after healing is a major challenge in the remission phase. In this context, remission is not synonymous with healed; it refers to a confirmed post-healing state in which the ulcer is closed, but
George Theodorakopoulos, David G. Armstrong   +1 more
doaj   +1 more source

3-D Generated Anatomic Custom Talar Cement Spacers: A Technical Tip and Literature Review

Foot & Ankle Orthopaedics, 2022
Category: Basic Sciences/Biologics; Hindfoot; Trauma Introduction/Purpose: Three dimensional printing is an actively emerging field within the realm of medical devices.
Kimberly K. Broughton MD, Bonnie Y. Chien MD, Derek S. Stenquist, Caroline Williams BA, Christopher P. Miller MD, John Y. Kwon MD   +5 more
doaj   +1 more source

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

Advanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan, Runze Yang, Ting Zhou, Tianhao Xu, Yongqi Li, Yuelin Hu, Minghao Ge, Lei Zhang, Xiong Lu, Chaoming Xie, Weili Fu   +10 more
wiley   +1 more source