Results 291 to 300 of about 106,775 (387)

Foot and ankle biomaterials: a comprehensive review of current applications, challenges, and future directions. [PDF]

J Orthop Translat
Elvin P, Sanchez A, Reyes AA, Andrade H, Karami M, Mir HT, La Fontaine J, Rodrigues D, Biguetti C.   +8 more
europepmc   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Advanced Science, Volume 13, Issue 19, 2 April 2026.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao   +11 more
wiley   +1 more source

Treatment for primary avascular necrosis of the lower limb in childhood. [PDF]

Cochrane Database Syst Rev
Ball S, Thomas R, Galloway AM, Davies LM, Gray K, Brennan S, Johnston RV, Williams N, Munns CF, Pacey V.   +9 more
europepmc   +1 more source

Limb Salvage Surgery and Wound Treatment in the Establishment of Globally Standardized Diabetes, Amputation, and Limb Salvage Centers to Address Lower Extremity Morbidity and Mortality in Thailand

, 2010
Gerit Mulder, Daniel K. Lee
openalex   +2 more sources

Neuronal Cholesterol Deficiency Mediated by Astrocytic SREBP2 Downregulation Leads to Postoperative Cognitive Dysfunction Through Impairment of Hippocampal Synaptic Plasticity and Excitatory Synaptic Transmission

Advanced Science, Volume 13, Issue 23, 23 April 2026.
The results showed that the reduction of plasma 24‐hydroxycholesterol (24‐OHC) was related to the cognitive decline in elderly surgical patients. Neuroinflammation induced by anesthesia and surgery significantly downregulated SREBP2 in hippocampal reactive astrocytes, resulting in reduced cholesterol synthesis.
He Huang, Chenrui Zhou, Chen Chen, Huimei Tang, Wei Dong, Jie Wan, Weiye Kang, Ao Sun, Yiqi Liu, Chunhui Jin, Xiaobin Lyu, Yankun Zhu, Chenghua Zhou, Yuqing Wu   +13 more
wiley   +1 more source

Distal Femoral Replacement in Young Adults with Traumatic Comminuted Distal Femur Fractures: A Report of Two Cases. [PDF]

J Orthop Case Rep
Sandaqji DO, Alharbi SS, Hajjar MH, Jamal RS.   +3 more
europepmc   +1 more source

Surgical outcomes of limb-salvage surgery with or without femoral vein reconstruction for soft tissue sarcomas of the thigh [PDF]

Wenquan Xu, Jinxin Hu, Xiaojun Zhu, Tao Zhang   +3 more
openalex   +1 more source

Nanotherapeutic Macrophage‐Neuro Reprogramming Through Immunometabolic Crosstalk Mitigates Sepsis‐Induced Lung Injury and Neurologic Damage

Advanced Science, Volume 13, Issue 24, 27 April 2026.
SJNPs co‐deliver JHU083 and spermine to reprogram macrophage–neuron immunometabolic crosstalk in sepsis. By suppressing pro‐inflammatory M1 polarization and promoting NGF‐mediated neurotrophic signaling, SJNPs preserve pulmonary neuronal integrity, alleviate lung injury, and improve survival in murine sepsis models.
Wenhui Wang, Yongrui Hai, Xintong Lu, Ye Chen, Bingjie Zhang, Renming Fan, Jiarui Dou, Jiaxin Yan, Shuo Fu, Wen Zhang, Junke Song, Gaofei Wei   +11 more
wiley   +1 more source

Transabdominal Surgical Management for Pouch Failure. [PDF]

Balkan Med J
Ajredini M, Erkan A, Desai A, Schwartzberg D, Gülmez M, Remzi FH.   +5 more
europepmc   +1 more source