Results 301 to 310 of about 106,775 (387)

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, Volume 13, Issue 23, 23 April 2026.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

Microbiological Characteristics and Clinical Outcomes of Periprosthetic Infections Following Oncologic Megaprosthetic Reconstruction: A Retrospective Cohort Study. [PDF]

Pathogens
Karampikas V, Goumenos S, Tsantes AG, Trikoupis IG, Gavriil P, Roustemis AG, Zikopoulos A, Petrakis V, Papadopoulos DV, Ioannou P, Savvidou O, Kontogeorgakos V, Papagelopoulos PJ.   +12 more
europepmc   +1 more source

Advanced Corneal Hydrogels: From Passive Replacement to Active Regeneration and Intelligent Interaction

Advanced Science, Volume 13, Issue 19, 2 April 2026.
This review charts the evolution of corneal hydrogels from passive replacements to active and intelligent systems, evaluating natural and synthetic materials while addressing design challenges such as transparency and strength. Advanced applications such as scarless wound healing, three‐dimensional bioprinting, and smart wearables are highlighted to ...
Xinwei Wang, Wen Zhou, Haotian Xue, Wenjun Xue, Guangping Gao, Bing Zhu, Hongyuan Song, Qingqiang Xu, Jing Zhao, Wei Shen   +9 more
wiley   +1 more source

Age Matters: A Systematic Review of Limb-Salvage Surgery Outcomes in Pediatric Versus Adult Osteosarcoma. [PDF]

Cureus
Alharbi MA, Aljeaid RF, Althebaity F, Alharthi HA, Al-Ghamdi L, Idris KW, Aledrissi A, Al-Harbi O, Bujbara A, Balobid R, Alshehri D, Al-Juhani A.   +11 more
europepmc   +1 more source

Repeated Disuse Atrophy Imprints a Molecular Memory in Skeletal Muscle: Transcriptional Resilience in Young Adults and Susceptibility in Aged Muscle

Advanced Science, Volume 13, Issue 23, 23 April 2026.
Repeated disuse imprints a molecular memory in skeletal muscle, conferring transcriptional resilience in young adults but exaggerated susceptibility in aged muscle, driven by epigenetic regulation of aerobic metabolism, mitochondrial and NAD+ pathways.
Daniel C. Turner, Truls Raastad, Max Ullrich, Stian F. Christiansen, Hazel Sutherland, James Boot, Eva Wozniak, Charles Mein, Emilie Dalbram, Jonas T. Treebak, Daniel J. Owens, David C. Hughes, Sue C. Bodine, Jonathan C. Jarvis, Adam P. Sharples   +14 more
wiley   +1 more source

PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation

Advanced Science, Volume 13, Issue 19, 2 April 2026.
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen, Zening Huang, Rui Chang, Wei Gao, Yajing Qiu, Bin Sun, Chen Hua, Xiaoxi Lin   +7 more
wiley   +1 more source

Interdisciplinary therapy of extremity soft tissue sarcomas: current evidence on systemic treatments and the role of reconstructive surgery. [PDF]

Innov Surg Sci
Steubing Y, Wallner C, Lehnhardt M, Celik E, Baues C, Schultheis B, Reinacher-Schick A, Füth M, Hinzmann J, Puscz F, Harenberg PS, Reinkemeier F.   +11 more
europepmc   +1 more source

A LDH‐Based Supramolecular Photosensitizer‐Functionalized Bioactive Glass Scaffold for Integrated Postoperative Osteosarcoma Recurrence Prevention and Bone Regeneration

Advanced Science, Volume 13, Issue 22, 17 April 2026.
An intercalation assembly strategy is proposed to construct a novel LDH‐based supramolecular photosensitizer, which exhibits outstanding reactive oxygen species generation activity under 1270 nm laser irradiation. The deposition of supramolecular photosensitizer onto the surface of bioactive glass scaffolds results in the development of an innovative ...
Tao Wang, Yixin Bian, Tingting Hu, Mengyang Li, Yuqin Tan, Yu Yang, Xiaolan Jian, Xisheng Weng, Chaoliang Tan, Ruizheng Liang   +9 more
wiley   +1 more source

Clinical practice guidelines for the diagnosis and treatment of patients with soft tissue sarcoma by the Spanish group for research in sarcomas (GEIS) [PDF]

Artigas, Vicenç, Bague, Silvia, Braña Vigil, Alejandro Francisco, García del Muro, Xavier, Álava, Enrique de   +4 more
core   +1 more source

ControlIt: A Universal Framework for Translational, Adaptive, and Online Brain–Computer Interfaces

Advanced Intelligent Systems, Volume 8, Issue 4, April 2026.
Brain–computer interfaces (BCIs) lack a unified platform that works across signals and algorithms. ControlIt, an open‐source, modular ROS2‐based BCI framework supporting electroencephalography (EEG), electrocorticography (ECoG), and spike‐based decoding across both classification and regression tasks is presented.
Wanlin Yang, Chenyang Li, Xinxiu Xu, Xindong Wang, Yongcheng Guo, Xiaoke Chai, Tianqin Cao, Jiuxiang Song, Nan Wang, Xueming Zhang, Yi Yang, Cong Zheng, He Cui   +12 more
wiley   +1 more source