Results 91 to 100 of about 6,209,872 (360)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

A New Anti-Windup Compensator Based on Quantitative Feedback Theory for an Uncertain Linear System with Input Saturation

open access: yesApplied Sciences, 2019
This paper devotes to the robust stability problem for an uncertain linear time invariant (LTI) feedback system with actuator saturation nonlinearity.
R. Jeyasenthil, Seung-Bok Choi
doaj   +1 more source

ISOCHRONOUS FAMILIES OF LIMIT CYCLES

open access: yesElectronic Journal of Differential Equations, 2018
In the work, the authors study dynamical systems with oscillations, and in particular they consider the frequency of such oscillations. An important problem is to know when the frequency of some oscillation does not depend on a parameter of the system.
Romina Cobiaga, Walter Reartes
openaire   +3 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Piecewise linear differential systems with an algebraic line of separation

open access: yesElectronic Journal of Differential Equations, 2020
We study the number of limit cycles of planar piecewise linear differential systems separated by a branch of an algebraic curve. We show that for each $n\in\mathbb{N}$ there exist piecewise linear differential systems separated by an algebraic curve ...
Armengol Gasull   +2 more
doaj  

Topology, vorticity, and limit cycle in a stabilized Kuramoto-Sivashinsky equation. [PDF]

open access: yesProc Natl Acad Sci U S A, 2022
Chen YC   +4 more
europepmc   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Bifurcations and multistability on the May-Holling-Tanner predation model considering alternative food for the predators

open access: yesMathematical Biosciences and Engineering, 2019
In this paper a modified May-Holling-Tanner predator-prey model is analyzed, considering an alternative food for predators, when the quantity of prey is scarce.
Eduardo González-Olivares   +3 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

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