Results 41 to 50 of about 1,331,530 (241)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Phylogenetic differences in content and intensity of periodic proteins [PDF]

, 2005
Many proteins exhibit sequence periodicity, often correlated with a visible structural periodicity. The statistical significance of such periodicity can be assessed by means of a chi-square-based test, with significance thresholds being calculated from ...
McEwan, N.R., Gatherer, D., Gatherer, Derek, McEwan, Neil R.   +3 more
core   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Limiting rotational period of neutron stars [PDF]

Physical Review D, 1992
Pulsars have been identified with the theoretical objects called neutron stars. The identification is convincing—but not proved. The short rotational periods of millisecond pulsars inform us that the average density (and, therefore, the central density) must be very high—higher than the density of nuclei (5.8).
openaire   +3 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Photonic-Crystal Josephson Traveling-Wave Parametric Amplifier

Physical Review X, 2020
A microwave amplifier combining noise performances as close as possible to the quantum limit with large bandwidth and high saturation power is highly desirable for many solid-state quantum technologies.
Luca Planat, Arpit Ranadive, Rémy Dassonneville, Javier Puertas Martínez, Sébastien Léger, Cécile Naud, Olivier Buisson, Wiebke Hasch-Guichard, Denis M. Basko, Nicolas Roch   +9 more
doaj   +1 more source

A CHIME/FRB Study of Burst Rate and Morphological Evolution of the Periodically Repeating FRB 20180916B

The Astrophysical Journal, 2023
FRB 20180916B is a repeating fast radio burst (FRB) with a 16.3 day periodicity in its activity. In this study, we present morphological properties of 60 FRB 20180916B bursts detected by CHIME/FRB between 2018 August and 2021 December.
Ketan R. Sand, Daniela Breitman, Daniele Michilli, Victoria M. Kaspi, Pragya Chawla, Emmanuel Fonseca, Ryan Mckinven, Kenzie Nimmo, Ziggy Pleunis, Kaitlyn Shin, Bridget C. Andersen, Mohit Bhardwaj, P. J. Boyle, Charanjot Brar, Tomas Cassanelli, Amanda M. Cook, Alice P. Curtin, Fengqiu Adam Dong, Gwendolyn M. Eadie, B. M. Gaensler, Jane Kaczmarek, Adam Lanman, Calvin Leung, Kiyoshi W. Masui, Mubdi Rahman, Ayush Pandhi, Aaron B. Pearlman, Emily Petroff, Masoud Rafiei-Ravandi, Paul Scholz, Vishwangi Shah, Kendrick Smith, Ingrid Stairs, David C. Stenning   +33 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

On the Euclidean action of de Sitter black holes and constrained instantons

SciPost Physics, 2023
We compute the on-shell Euclidean action of Schwarzschild-de Sitter black holes, and take their contributions in the gravitational path integral into account using the formalism of constrained instantons.
Edward K. Morvan, Jan Pieter van der Schaar, Manus R. Visser
doaj   +1 more source