Results 51 to 60 of about 185,697 (284)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Observation of Dynamical Super Efimovian Expansion in a Unitary Fermi Gas

open access: yes, 2017
We report an observation of a dynamical super Efimovian expansion in a two-component strongly interacting Fermi gas by engineering time dependent external harmonic trap frequencies.
Deng, Shujin   +5 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Limit cycle periods in damage detection

open access: yesMechanical Systems and Signal Processing, 2022
This paper introduces a damage detection scheme based on changes in the period of limit cycles (LCs) realized by nonlinear output feedback. The parameterized feedback law is selected to make the dynamic equilibrium of the actuated coordinate approximate that of a generalized van der Pol oscillator and potential model-related difficulties are avoided by
Bernal, Dionisio   +2 more
openaire   +2 more sources

Superconductivity, Superfluidity and Holography

open access: yes, 2013
This is a concise review of holographic superconductors and superfluids. We highlight some predictions of the holographic models and the emphasis is given to physical aspects rather than to the technical details, although some references to understand ...
Salvio, Alberto
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Can Theta/N Dependence for Gluodynamics be Compatible with 2 pi Periodicity in Theta ?

open access: yes, 1998
In a number of field theoretical models the vacuum angle \theta enters physics in the combination \theta/N, where N stands generically for the number of colors or flavors, in an apparent contradiction with the expected 2 \pi periodicity in \theta.
A. Kovner   +43 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Limiting rotational period of neutron stars [PDF]

open access: yesPhysical Review D, 1992
Pulsars have been identified with the theoretical objects called neutron stars. The identification is convincing—but not proved. The short rotational periods of millisecond pulsars inform us that the average density (and, therefore, the central density) must be very high—higher than the density of nuclei (5.8).
openaire   +3 more sources

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

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