Results 41 to 50 of about 495,171 (257)

Research and application of low oil-water ratio organoclay-free oil-based drilling fluid technology [PDF]

E3S Web of Conferences
This paper introduces the formation and application of a low oil-water ratio organoclay-free oil-based drilling fluid. Shale oil and gas are important alternative energy sources.
Shi He, Ni Xiaoxiao, Wang Xiaofei, Yang Zheng, Wang Jianhua, Cheng Rongchao, Yan Lili, Zhang Jiaqi, Yang Haijun, Cui Xiaobo, Zhang Lining   +10 more
doaj   +1 more source

Mass thickness detection and verification for radiation processing products based on X-ray detection technology

Fushe yanjiu yu fushe gongyi xuebao, 2021
To quickly obtain the mass thickness and predetermine dose distribution of electron beam irradiated products, a new detection method was developed based on X-ray detection technology.
LIU Yanqin, QIN Huaili, LIANG Aifeng, KUANG Shan, YANG Guang, WANG Qiang, LIU Jingjing   +6 more
doaj   +1 more source

Administering Blinatumomab via Continuous Intravenous Infusion in Pediatric Patients—A Single‐Institution Retrospective Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab, a CD19xCD3 bispecific T‐cell engager, has become standard therapy for children with de novo B‐cell acute lymphoblastic leukemia (B‐ALL). This retrospective review describes the experience of blinatumomab administration in pediatric patients.
Julia M. Hurley, Ryleigh Krueger, Kellie Joyce, James Stanley, Mary Waskerwitz‐Freyer, Marielle Klunder, David J. Hoogstra   +6 more
wiley   +1 more source

Combining fruquintinib with TAS-102 as a promising strategy: antitumor activity in preclinical colorectal and gastric cancer xenograft models

BMC Cancer
Background The combination of bevacizumab and TAS-102 has emerged as a treatment option for metastatic colorectal cancer (CRC). Bevacizumab is an anti-VEGF-A antibody, and TAS-102 is a cytotoxic nucleotide analog.
Takahito Hara, Megumi Morimoto, Masaaki Kakehi, Momoko Kamedani, Miyu Nakayama, Syunsuke Yamamoto, Tsuyoshi Osaka, Junpei Soeda, Hideaki Bando, Takayuki Yoshino   +9 more
doaj   +1 more source

Prospects for the use of inulin and its modifications in the food, cosmetic and pharmaceutical industries

Vestnik MGTU
The paper contains a review of modern data on the use of the polysaccharide inulin and its modifications in various industries. Data on the use of native inulin in various food technologies have been presented.
Skorodumov A. S., Nesterov E. D., Gorn D. S., Barkanov A. V., Shanenko E. F.   +4 more
doaj   +1 more source

Application Function Design for UPFC Online Operation Optimization Decision-making

Zhongguo dianli, 2021
Due to the lack of guide tools for UPFC real-time operation optimization, the powerful power flow control capability of UPFC cannot be played flexibly.
Feng LI, Huimin PENG, Huling YUAN, Fangru WAN, Tiangang HUANG, Wei LI   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Effects of an OX2R agonist on migration and removal of tau from mouse brain

Scientific Reports
Pathological proteins including tau are produced in neurons and released into interstitial fluid (ISF) in a neural activity-dependent manner during wakefulness.
Michiko Terada, Kayo Mitsukawa, Masanori Nakakariya, Tatsuki Koike, Haruhide Kimura   +4 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source