Results 21 to 30 of about 3,204 (237)

Obacunone inhibits microglia‐mediated neuroinflammation and ischemic injury by targeting MAPK1 [PDF]

open access: yesAlzheimers Dement
Abstract Background Microglia‐mediated neuroinflammation plays a critical role in the pathogenesis of ischemic stroke and represents as a promising target for stroke treatment. Obacunone (OB), a triterpenoid limonin extracted from natural citrus plants, exhibits anti‐inflammatory, antioxidant and anti‐cancer properties.
Zhu X, Huang J, Xu Y.
europepmc   +2 more sources

Limonin, an AMPK Activator, Inhibits Hepatic Lipid Accumulation in High Fat Diet Fed Mice

open access: yesFrontiers in Pharmacology, 2022
NAFLD is the most prevalent liver disease in human history. The treatment is still limited yet. In the current study, we reported that limonin inhibited hepatic lipid accumulation and fatty acid synthesis in HFD fed mice.
Si-wei Wang   +7 more
doaj   +1 more source

Limonin Isolated From Pomelo Seed Antagonizes Aβ25-35-Mediated Neuron Injury via PI3K/AKT Signaling Pathway by Regulating Cell Apoptosis

open access: yesFrontiers in Nutrition, 2022
Pomelo seed as a by-product from pomelo consumption is rich in bioactive compounds, however, a huge volume of pomelo seed was disposed as wastes, the comprehensive utilization of pomelo seed could not only generate valued-added products/ingredients, but ...
Yuanxin Qiu   +6 more
doaj   +1 more source

Limonin Derivatives via Hydrogenation: Structural Identification and Anti-Inflammatory Activity Evaluation

open access: yesApplied Sciences, 2022
Limonin is a natural compound which is rich in the fruit of various plants of the Rutaceae family and demonstrated to have a wide range of biological activities.
Jingguo Yang, Yuhong Hu, Kuan Chang
doaj   +1 more source

Limonin ameliorates indomethacin‐induced intestinal damage and ulcers through Nrf2/ARE pathway

open access: yesImmunity, Inflammation and Disease, 2023
Background Nonsteroidal anti‐inflammatory drugs (NSAIDs) can cause intestinal damage and ulcers and the incidence is increasing. Limonin plays an important role in the regulation of inflammatory diseases, but it has not been reported in the treatment of ...
Bo Jia   +4 more
doaj   +1 more source

Metabolomic Analysis of Phytochemical Compounds from Ethanolic Extract of Lime (Citrus aurantifolia) Peel and Its Anti-Cancer Effects against Human Hepatocellular Carcinoma Cells

open access: yesMolecules, 2023
Lime peels are food waste from lime product manufacturing. We previously developed and optimized a green extraction method for hesperidin-limonin-rich lime peel extract. This study aimed to identify the metabolomics profile of phytochemicals and the anti-
Pakkapong Phucharoenrak   +2 more
doaj   +1 more source

Limonin Enhances the Antifungal Activity of Eugenol Nanoemulsion against Penicillium Italicum In Vitro and In Vivo Tests

open access: yesMicroorganisms, 2021
Penicillium italicum, the cause of citrus blue mold, is a pathogenic fungus that seriously affects the postharvest quality of citrus fruit and causes serious economic loss.
Yi Li, Runan Zhao, Yan Li, Zhiqin Zhou
doaj   +1 more source

Effects of limonin treatment on the survival of random skin flaps in mice

open access: yesFrontiers in Surgery, 2023
Random skin flap is commonly used in plastic and reconstructive surgery, however, distal part of skin flap often occurs ischemia and necrosis. Limonin, with bioactivities of anti-inflammation, anti-apoptosis and anti-oxidative stress, may be effective ...
Ting Zhang   +7 more
doaj   +1 more source

The chemistry and pharmacology of citrus limonoids [PDF]

open access: yes, 2016
Citrus limonoids (CLs) are a group of highly oxygenated terpenoid secondary metabolites found mostly in the seeds, fruits and peel tissues of citrus fruits such as lemons, limes, oranges, pumellos, grapefruits, bergamots, and mandarins.
Ahmad   +37 more
core   +3 more sources

Kandungan Flavonoid Dan Limonoid Pada Berbagai Fase Pertumbuhan Tanaman Jeruk Kalamondin (Citrus Mitis Blanco) Dan Purut (Citrus Hystrix Dc.) [PDF]

open access: yes, 2010
. Devy, N.F., F. Yulianti, and Andrini. 2010. Flavonoid and Limonoid Contents in Every GrowthPhase of Kalamondin (Citrus mitis Blanco) and Purut (Citrus hystrix Dc.). Citrus contains secondary metabolitessuch as flavonoid, carotenoid, and limonoid, which
Andrini, A. (Andrini)   +2 more
core   +2 more sources

Home - About - Disclaimer - Privacy