Results 21 to 30 of about 4,052 (247)
Zhongliu Fangzhi Yanjiu, 2023 Objective To investigate the influence of limonin on the malignant biological behavior of non-small cell lung cancer (NSCLC) cells by regulating the protein tyrosine kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) signaling ...
HU Huijie, ZHENG Xiaolu, LEI Lifeng
doaj +1 more source
Limonin, an AMPK Activator, Inhibits Hepatic Lipid Accumulation in High Fat Diet Fed Mice
Frontiers in Pharmacology, 2022 NAFLD is the most prevalent liver disease in human history. The treatment is still limited yet. In the current study, we reported that limonin inhibited hepatic lipid accumulation and fatty acid synthesis in HFD fed mice.
Si-wei Wang +7 more
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Frontiers in Nutrition, 2022 Pomelo seed as a by-product from pomelo consumption is rich in bioactive compounds, however, a huge volume of pomelo seed was disposed as wastes, the comprehensive utilization of pomelo seed could not only generate valued-added products/ingredients, but ...
Yuanxin Qiu +6 more
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Applied Sciences, 2022 Limonin is a natural compound which is rich in the fruit of various plants of the Rutaceae family and demonstrated to have a wide range of biological activities.
Jingguo Yang, Yuhong Hu, Kuan Chang
doaj +1 more source
Molecules, 2023 Lime peels are food waste from lime product manufacturing. We previously developed and optimized a green extraction method for hesperidin-limonin-rich lime peel extract. This study aimed to identify the metabolomics profile of phytochemicals and the anti-
Pakkapong Phucharoenrak +2 more
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Obacunone inhibits microglia‐mediated neuroinflammation and ischemic injury by targeting MAPK1 [PDF]
Alzheimers DementAbstract Background Microglia‐mediated neuroinflammation plays a critical role in the pathogenesis of ischemic stroke and represents as a promising target for stroke treatment. Obacunone (OB), a triterpenoid limonin extracted from natural citrus plants, exhibits anti‐inflammatory, antioxidant and anti‐cancer properties.
Zhu X, Huang J, Xu Y.
europepmc +2 more sources
Microorganisms, 2021 Penicillium italicum, the cause of citrus blue mold, is a pathogenic fungus that seriously affects the postharvest quality of citrus fruit and causes serious economic loss.
Yi Li, Runan Zhao, Yan Li, Zhiqin Zhou
doaj +1 more source
Limonin, a natural ERK2 agonist, protects against ischemic acute kidney injury
International Journal on Biological Sciences, 2023 Acute kidney injury (AKI) is a refractory clinical syndrome with limited effective treatments. Amid AKI, activation of the extracellular signal-regulated kinase (ERK) cascade plays a critical role in promoting kidney repair and regeneration.
Xianke Zhou +15 more
semanticscholar +1 more source
The chemistry and pharmacology of citrus limonoids [PDF]
, 2016 Citrus limonoids (CLs) are a group of highly oxygenated terpenoid secondary metabolites found mostly in the seeds, fruits and peel tissues of citrus fruits such as lemons, limes, oranges, pumellos, grapefruits, bergamots, and mandarins.
Ahmad +37 more
core +3 more sources
Quality control of natural product medicine and nutrient supplements [PDF]
, 2013 10.1155/2013/182573Journal of Analytical Methods in ...
Bai, S. +5 more
core +4 more sources