Results 21 to 30 of about 358 (121)
International Journal of Food Science, Volume 2026, Issue 1, 2026.Citrus aurantiifolia is widely used as food, beverage, and herbal medicine, but produces significant waste, about 50% of the fruit, especially the peel. The peel is rich in phenolic compounds and flavonoids, but the bitterness of the flavonoids limits its widespread application. This study is aimed at masking the bitter taste of C.
Yesi Desmiaty +7 more
wiley +1 more source
Exploring the Neuroprotective Promise of Functional Fruit Phytochemicals
Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.Neurodegenerative diseases, including Alzheimer’s disease, represent a significant global clinical challenge, since existing treatments primarily manage symptoms rather than addressing the complex and multifactorial underlying pathologies. Functional fruits, including both their edible and nonedible parts, are rich in bioactive phytochemicals such as ...
Tebalelo Lehlaleroa +5 more
wiley +1 more source
Obacunone inhibits microglia‐mediated neuroinflammation and ischemic injury by targeting MAPK1
Alzheimer's &Dementia, Volume 21, Issue S5, December 2025.Abstract Background Microglia‐mediated neuroinflammation plays a critical role in the pathogenesis of ischemic stroke and represents as a promising target for stroke treatment. Obacunone (OB), a triterpenoid limonin extracted from natural citrus plants, exhibits anti‐inflammatory, antioxidant and anti‐cancer properties.
Xiaolei Zhu, Jing Huang, Yun Xu
wiley +1 more source
The emerging role of Nrf2 in heart failure: From cardioprotection to therapeutic approaches
ESC Heart Failure, Volume 12, Issue 6, Page 4000-4020, December 2025.Nrf2 signalling is impaired in heart failure, contributing to oxidative stress, mitochondrial dysfunction, and ferroptosis, which drive neurohormonal activation, inflammation, and ischaemia‐reperfusion injury. This loss of Nrf2 activity exacerbates hypertension, diabetic cardiomyopathy, and cardiotoxicity, accelerating progression to overt heart ...
Emiliano Fiori +9 more
wiley +1 more source
Lactylation in cancer: Advances and opportunities for treatment resistance
Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.Aberrant lactylation plays a crucial role in the development of resistance to chemotherapy, immunotherapy, targeted therapy, and radiotherapy. Strategies to overcome this resistance include the inhibition of key glycolytic enzymes, targeting lactate transporters, synergistic therapeutic approaches, and the inhibition of specific site.
Keke Xu +10 more
wiley +1 more source
A Multifaceted Review on Neodiosmin In Planta Distribution, (Bio)synthesis, Food and Health Effects
Future Postharvest and Food, Volume 2, Issue 3, Page 237-247, September 2025.ABSTRACT Neodiosmin (NEO) is a major glycosylated flavone that is derived from the bitter flavanone neo‐hesperidin in citrus fruits including orange, lime, and lemon. One of the most important features of NEO is that it exerts a notable debittering effect on plant flavonoids justifying its wide use as a food additive.
Yuxuan Zhao +4 more
wiley +1 more source
Food Science &Nutrition, Volume 13, Issue 9, September 2025.Citri Sarcodactylis Fructus (CSF) has been shown to exhibit anti‐inflammatory, antioxidant, and anti‐obesity effects. However, its impact on the progression of acute lung injury (ALI) remains unclear. This study reveals that CSF alleviates LPS‐induced ALI by inhibiting NF‐κB signaling and NLRP3 inflammasome activation‐mediated inflammatory response ...
Zhuohui Luo +4 more
wiley +1 more source
Functional Polymers and Their Nanocomposites for Sustainable Packaging Applications
Macromolecular Materials and Engineering, Volume 310, Issue 9, September 2025.This study provides recent advances and knowledge gaps related to developing plastics‐based sustainable packaging materials across various segments, focusing on the intervention of functionality and nanotechnology and their impact on sustainability. Abstract This study explores recent advances and knowledge gaps in developing sustainable plastics‐based
Ritima Banerjee +2 more
wiley +1 more source
Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.Citrus sinensis seed powder at 0.5% in broiler diets optimized caecal bacterial populations, while 4% supplementation increased IgG levels compared to antibiotic use. These findings suggest potential benefits of orange seeds as a phytogenic feed additive, despite the need for further studies on their bioactive compounds and mechanisms.
Tchilabalo Parobali +7 more
wiley +1 more source
Food Science &Nutrition, Volume 13, Issue 6, June 2025.Guang Chenpi (GCP), a dual‐use food and medicine, requires optimal storage to maintain quality. Studies using UV, HPLC‐PDA, and GC–MS showed low temperature and humidity hinder aging, while high levels accelerate compound transformation but reduce key components like hesperidin. PE bags preserve flavonoids better than gunny bags.
Mengdie Peng +7 more
wiley +1 more source