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Recombinant Factor C as an In Vitro Assay for the Residual Pathogenicity Evaluation of Veterinary Autogenous Vaccines [PDF]
Veterinary SciencesBackground: Veterinary autogenous vaccines, similar to all injectable pharmaceutical products, must be tested to assess endotoxin concentrations. The Limulus Amebocyte Lysate Test (LAL test) is widely used in in vitro quality control assays for endotoxin
Antonella Di Paolo +6 more
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Are Severe Mastitis Cases in Dairy Cows Associated with Bacteremia?
Animals, 2021 The objective of this study was to investigate the occurrence of bacteremia in dairy cows with severe mastitis. Milk samples were collected from affected udder quarters, and corresponding blood samples were collected from dairy cows with severe mastitis ...
Julia Brennecke +3 more
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Limulus test and meningitis. [PDF]
BMJ, 1977 info:eu-repo/semantics ...
Clumeck, Nathan +2 more
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A method to prevail false positive responses due to excess cations and viscous nature of Radiopharmaceuticals in Limulus Amebocyte Lysate Gel Clot test [PDF]
Asia Oceania Journal of Nuclear Medicine and Biology, 2022 Objective(s): Bacterial endotoxin test (BET) for detection and quantification of endotoxin in radiopharmaceuticals (RPs), used for therapy or diagnosis, is prerequisite to administration in patients.
Arpit Mitra +3 more
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Capture of lipopolysaccharide (endotoxin) by the blood clot: a comparative study. [PDF]
PLoS ONE, 2013 In vertebrates and arthropods, blood clotting involves the establishment of a plug of aggregated thrombocytes (the cellular clot) and an extracellular fibrillar clot formed by the polymerization of the structural protein of the clot, which is fibrin in ...
Margaret T Armstrong +2 more
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Recombinant bacterial endotoxin testing: a proven solution
BioTechniques, 2021 Testing of parenteral pharmaceuticals and medical devices for pyrogens (fever-inducing substances) is critical to patient safety. The original rabbit pyrogen test has largely been replaced by different bacterial endotoxin tests based on Limulus amebocyte
Brendan Tindall +2 more
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Prokaryotic expression of glucans binding protein and application for detecting invasive fungal infection [PDF]
Jichu yixue yu linchuang, 2022 Objective To explore the potential application of glucans binding protein (GBP) in the detection of soluble glucans from serum sampled from patients with invasive fungal infection (IFI). Methods The prokaryotic plasmid pET30a-GBP252-668 coding for 252 to
ZHU Li-ru, HUANG You-ming, ZHANG Hong-xiang, ZHOU Fa-you, TANG Xiao-lei
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Bacteremia in Severe Mastitis of Dairy Cows
Microorganisms, 2023 The aim of this cross-sectional study was to investigate the occurrence of bacteremia in severe mastitis cases of dairy cows. Milk and corresponding blood samples of 77 cases of severe mastitis were bacteriologically examined. All samples (milk and blood)
Isabel Krebs +4 more
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Frontiers in Marine Science, 2020 Endotoxin testing is a vital part of quality and safety control in pharmaceutical production. The primary method for this testing in North America and Europe is the limulus amebocyte lysate (LAL) test, a critical component of which is the blood of ...
Richard Gorman
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Human Vaccines & Immunotherapeutics, 2021 Outer membrane vesicles (OMV) are exosomes naturally released from the surface of Gram-negative bacteria. Since the ’80s, OMVs have been proposed as powerful vaccine platforms due to their intrinsic self-adjuvanticity and ability to present multiple ...
Omar Rossi +2 more
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