Results 21 to 30 of about 14,293 (184)
The endotoxin test is based on the reaction between Limulus Amebocyte Lysate (LAL) and the lipopolysaccharides of Gram-negative bacteria. In this study, we sought to identify factors that interfere with the LAL testing of radiopharmaceuticals and ...
Jun Young PARK
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The Limulus test in experimental and clinical endotoxaemia
Abstract Gram-negative septicaemia is being recognized (is an increasingly common cause of mortality in hospital practice. In this paper the value of a simple and rapid test which can be used to detect the presence of circulating endotoxins is assessed in experimental and clinical situations.
D P, Fossard, V V, Kakkar
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Endotoxins Affecting Human Health during Agricultural Practices: An Overview
Agricultural operations and the processing sector generate dust laden with endotoxin in the workplace. Endotoxin, a pro-inflammatory agent, has adverse effects on health, especially in the lungs, as exposure to endotoxin reduces lung function capacity ...
B. Surya Kumar Chhetry +3 more
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Validation of moist and dry heat processes used for sterilization and depyrogenation during ampoules manufacturing [PDF]
Pyrogens are fever-producing substances, which are metabolic products of microorganisms and most potent pyrogens are the endotoxins. Depyrogenation can be defined as the elimination of all pyrogenic substances which is an important part of the ...
Ahmed Rashed +3 more
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An expert review on current approaches for endotoxin detection in various biological products
Endotoxin is heat-stable lip polysaccharide (LPS) present in the outer membrane of the cell wall of Gram-negative bacteria. All parenteral preparations, as well as tissue implants, must be with no pyrogenic level of endotoxin or other related materials ...
Mohammed A. Elkhateeb +2 more
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Improvement of the Micromethod for the Limulus Lysate Test [PDF]
AbstractFrauch's micro‐slide method was improved to facilitate the endpoint‐determination of the Limulus test. Two precise observations, by inverted phase contrast microscopy and with a staining procedure, were newly performed as additions to the slide test.
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Deaths due to invasive fungal disease (IFD) have been increasing every year. Early and rapid detection is important to reduce the mortality rate associated with IFD.
Fang Cui +3 more
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As injectable therapeutics, snake antivenoms must meet specifications for endotoxin content. The Limulus amebocyte lysate (LAL) test was used to evaluate the endotoxin content in several commercially available antivenoms released for clinical use. It was
Gabriela Solano +7 more
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Measurement of endotoxins with the limulus test in burned patients [PDF]
SUMMARYHigh titres of endotoxin as measured by the Limulus test were usually found in burned patients who had raised body temperatures, and were colonized with gram-negative bacteria; also some infected patients showed raised endotoxin without a raised temperature.Patients vaccinated with an antipseudomonas vaccine rarely showed endotoxin in their ...
R J, Jones, E A, Roe
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Exposure to 305 nm PP NPs significantly disrupts the airway barrier‐on‐chip, reducing TEER, suppressing ZO‐1/ACE2 expression, and triggering ROS‐mediated apoptosis. In biological media, PP NPs exhibit a biphasic adsorption pattern, leading to the formation of a protein corona that increases their size to 364 nm.
Omur Sert +9 more
wiley +1 more source

