Results 11 to 20 of about 14,293 (184)
Asian Journal of Pharmaceutical Sciences, 2018 Endotoxin detection is an important step in drug characterization. Herein we found that a chemotherapeutic drug nanoformulation composed of irinotecan hydrochloride (CPT-11) and an amphiphilic molecule DSPE-mPEG2000 can interfere with the limulus ...
Yanan Jin +9 more
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Determination of endotoxins in sugar with the Limulus test [PDF]
Applied and Environmental Microbiology, 1979 The Limulus amebocyte lysate test has been used for determination of pyrogens in sugar of different qualities. All the samples of domestic white sugar and beet raw sugar produced in Sweden during 1976 had a very low content of endotoxins, less than 10 ng/g of sugar. Imported cane raw sugar was, however, highly contaminated.
G, Haskå, R, Nystrand
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Scientific Reports, 2021 Endotoxin neutralization, caused by plasma components, makes it difficult to detect endotoxins in human blood. In this study, we investigated which factors influence the recovery of endotoxins using limulus ameobocyte lysate (LAL)-based assays.
Stephan Harm +3 more
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Assessment of Limulus Test for Detecting Endotoxaemia [PDF]
BMJ, 1974 The occurrence of endotoxaemia in 46 surgical patients has been investigated using a sensitive preparation of limulus lysate. Altogether 23 patients with local and systemic Gram-negative infections were shown to have endotoxaemia. An overt infection is not a prerequisite for a positive limulus test result, since endotoxin can be absorbed via the ...
D P, Fossard, V V, Kakkar, P A, Elsey
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Innate Immunity, 2022 Pyrogens are classified in two groups, endotoxin pyrogens and non-endotoxin pyrogens (NEPs). The presence of either in parenteral pharmaceuticals or medical devices can cause severe harm to subjects, and when occurring in combination, synergistic ...
Shabnam Solati +2 more
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Arachnologische Mitteilungen, 2015 The zoological collection of the National Museum, Prague (NMP) contains spirit (juvenile) as well as dry (mostly adult) specimens of horseshoe crabs (Xiphosura).
Dolejš, Petr, Vaňousová, Kateřina
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Ciência Rural, 2007 Realizou-se a avaliação de pirogênios em produtos veterinários de uso parenteral, pelo método da hipertermia em coelhos, calculando-se, para o teste das amostras, doses com concentrações de três a sete vezes superiores à terapêutica.
Thiago Barth +3 more
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Scientific Reports, 2021 The exquisite specificity of Toll-like receptors (TLRs) to sense microbial molecular signatures is used as a powerful tool to pinpoint microbial contaminants.
Clovis H. T. Seumen +3 more
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Detection of Endotoxin Contamination of Graphene Based Materials Using the TNF-α Expression Test and Guidelines for Endotoxin-Free Graphene Oxide Production. [PDF]
PLoS ONE, 2016 Nanomaterials may be contaminated with bacterial endotoxin during production and handling, which may confound toxicological testing of these materials, not least when assessing for immunotoxicity.
Sourav P Mukherjee +8 more
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Insects, 2022 The medical device is a nerve conduit entirely made of Bombyx mori silk fibroin. It is a tubular scaffold used for repairing peripheral nerve gaps, whose function is to protect the severed nerves and to favor their natural healing process.
Giulia Alessandra Bassani +7 more
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