Results 51 to 60 of about 4,881,979 (331)
Alu and LINE-1 methylation and lung function in the normative ageing study [PDF]
, 2012 Objectives: To investigate the association between methylation of transposable elements Alu and long-interspersed nuclear elements (LINE-1) and lung function. Design: Cohort study. Setting: Outpatient Veterans Administration facilities in greater Boston,
Baccarelli, Andrea +10 more
core +2 more sources
Identifying the genetic basis for resistance to avian influenza in commercial egg layer chickens
Animal, 2018 Two highly pathogenic avian influenza (HPAI) outbreaks have affected commercial egg production flocks in the American continent in recent years; a H7N3 outbreak in Mexico in 2012 that caused 70% to 85% mortality and a H5N2 outbreak in the United States ...
W. Drobik-Czwarno +6 more
doaj +1 more source
The Reverse Transcriptase Encoded by LINE-1 Retrotransposons in the Genesis, Progression, and Therapy of Cancer [PDF]
, 2016 In higher eukaryotic genomes, Long Interspersed Nuclear Element 1 (LINE-1) retrotransposons represent a large family of repeated genomic elements. They transpose using a reverse transcriptase (RT), which they encode as part of the ORF2p product.
Chiara De Luca +2 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Characterizing stressful events reported by childhood cancer survivors experienced throughout the lifespan may help improve trauma‐informed care relevant to the survivor experience. Methods Participants included 2552 survivors (54% female; 34 years of age) and 469 community controls (62% female; 33 years of age) from the St.
Megan E. Ware +13 more
wiley +1 more source
Retrotransposon-Encoded Reverse Transcriptase in the Genesis, Progression and Cellular Plasticity of Human Cancer [PDF]
, 2011 LINE-1 (Long Interspersed Nuclear Elements) and HERVs (Human Endogenous Retroviruses) are two families of autonomously replicating retrotransposons that together account for about 28% of the human genome.
Matteucci, C +2 more
core +2 more sources
Multi-functional BST2/tetherin against HIV-1, other viruses and LINE-1
Frontiers in Cellular and Infection Microbiology, 2022 Bone marrow stromal cell antigen 2 (BST2), also known as CD317, HM1.24, or tetherin, is a type II transmembrane glycoprotein. Its expression is induced by IFN-I, and it initiates host immune responses by directly trapping enveloped HIV-1 particles onto ...
Yifei Zhao +7 more
doaj +1 more source
Do Small RNAs Interfere With LINE‐1? [PDF]
BioMed Research International, 2006 Long interspersed elements (LINE‐1 or L1) are the most active transposable elements in the human genome. Due to their high copy number and ability to sponsor retrotransposition of nonautonomous RNA sequences, unchecked L1 activity can negatively impact the genome by a number of means.
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij +11 more
wiley +1 more source
Regulation of LINE-1 in mammals [PDF]
, 2017 Transposable elements (TEs) are mobile DNA elements that represent almost half of the human genome. Transposition of TEs has been implicated as a source of genome evolution and acquisition of new traits but also as an origin of diseases.
Bodak, Maxime +2 more
core
Instability Mechanism of Cavity-Bearing Formation under Tunnel Excavation Disturbance
Advances in Civil Engineering, 2020 Urban subway construction inevitably causes disturbances to the rock strata. It can even cause ground collapse accidents when construction encounters a bad geological body in the stratum.
Tao Liu +5 more
doaj +1 more source