Results 71 to 80 of about 4,813,932 (329)

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

Folate Network Genetic Variation, Plasma Homocysteine, and Global Genomic Methylation Content: A Genetic Association Study [PDF]

, 2013
Background: Sequence variants in genes functioning in folate-mediated one-carbon metabolism are hypothesized to lead to changes in levels of homocysteine and DNA methylation, which, in turn, are associated with risk of cardiovascular disease.
Baccarelli, Andrea, Bollati, Valentina, Cassano, Patricia A, Clark, Andrew G., Gaziano, John Michael, Litonjua, Augusto Ampil, Schwartz, Joel David, Stover, Patrick J, Tucker, Katherine L, Weiss, Scott Tillman, Wells, Martin T, Wernimont, Susan M   +11 more
core   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source

FILTER-UNIT PULSE AND FLUCTUATING NOISE [PDF]

Vestnik KRAUNC: Fiziko-Matematičeskie Nauki, 2012
The technique and algorithms for identifying structural components of non-sinusoidal voltage and current signals in the ship power system. The skeleton diagram and useful model of active compensator conducted emissions on the basis of wavelet transform.
T.S. Goreva, S.E. Kuznetsov, N.N. Pornjagin   +2 more
doaj   +1 more source

Precipitation Extremes and Their Synoptic Models in the Northwest European Sector of the Arctic during the Cold Season

Atmosphere, 2022
Precipitation extrema over the Barents Sea and the neighbouring locations in Europe were analysed using data obtained from station observations and a highly detailed ERA5 re-analysis dataset.
Alexander Kislov, Tatiana Matveeva, Uliana Antipina   +2 more
doaj   +1 more source

Silybin Showed Higher Cytotoxic, Antiproliferative, and Anti-Inflammatory Activities in the CaCo Cancer Cell Line while Retaining Viability and Proliferation in Normal Intestinal IPEC-1 Cells [PDF]

, 2023
Dominika Faixová, Marek Ratvaj, Ivana Cingeľová Maruščáková, Gabriela Hrčková, Viera Karaffová, Z. Faixová, Dagmar Mudroňová   +6 more
openalex   +1 more source

LINE-1 (L1) Lineages in the Mouse [PDF]

Molecular Biology and Evolution, 2000
Recently, a rapidly amplifying family of mouse LINE-1 (L1) has been identified and named T(F). The evolutionary context surrounding the derivation of the T(F) family was examined through phylogenetic analysis of sequences in the 3' portion of the repeat.
S C, Hardies, L, Wang, L, Zhou, Y, Zhao, N C, Casavant, S, Huang   +5 more
openaire   +2 more sources

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

LINE-1 hypomethylation in gastric cancer, detected by bisulfite pyrosequencing, is associated with poor prognosis [PDF]

, 2012
BACKGROUND: Genome-wide DNA hypomethylation plays an important role in genomic instability and carcinogenesis. DNA methylation in the long interspersed nucleotide element-1, L1 (LINE-1) repetitive element is a good indicator of the global DNA methylation
Asuka Murata, Hideo Baba, Hironobu Shigaki, Keisuke Miyake, Masaaki Iwatsuki, Masayuki Watanabe, Shiro Iwagami, Takatsugu Ishimoto, Yoshifumi Baba   +8 more
core   +1 more source

Genomic Deletions Created upon LINE-1 Retrotransposition [PDF]

Cell, 2002
LINE-1 (L1) retrotransposition continues to impact the human genome, yet little is known about how L1 integrates into DNA. Here, we developed a plasmid-based rescue system and have used it to recover 37 new L1 retrotransposition events from cultured human cells.
Gilbert, Nicolas, Lutz-Prigge, Sheila, Moran, John V.   +2 more
openaire   +2 more sources