Results 101 to 110 of about 11,224,100 (302)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
A novel label-free electrochemical immunosensor for the detection of heat shock protein 70 of lung adenocarcinoma cell line following paclitaxel treatment using l-cysteine-functionalized Au@MnO2/MoO3 nanocomposites. [PDF]
RSC Adv, 2023 Chen YA +7 more
europepmc +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Near-surface motion modeling and wave-following control of AUVs
Zhongguo Jianchuan YanjiuObjectiveTo address the covert communication requirements of autonomous underwater vehicles (AUVs), this study proposes a near-surface communication mode equipped with a foldable antenna.MethodsUtilizing strip theory to predict the wave forces of regular
Yi WANG +3 more
doaj +1 more source
, 2012 We continue our study of the physical properties of the recurrent nova T Pyx, focussing on the structure of the ejecta in the nebular stage of expansion during the 2011 outburst.
Aquino, I. De Gennaro +6 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Further Criteria for the Existence of Steady Line-Driven Winds
, 2004 In Paper I, we showed that steady line-driven disk wind solutions can exist by using "simple" models that mimic the disk environment. Here I extend the concepts introduced in Paper I and discuss many details of the analysis of the steady/unsteady nature ...
Hillier D. J. +2 more
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The NSINIC on-line system [PDF]
The NSI NIC on-line system is described in the form of view graphs. The following subject areas are covered: NSI history; the ADFTO's other on-line services; the current system; and the next generation of NSI ...
Lev, Brian
core +1 more source
Early Life Relict Feature in Peptide Mass Distribution [PDF]
, 2008 Molecular mass of a biomolecule is characterized in mass spectroscopy by the monoisitopic mass M~mono~ and the average isotopic mass M~av~. We found that peptide masses mapped on a plane made by two parameters derived from M~mono~ and M~av~ form a ...
Alexander R. Zubarev +4 more
core +1 more source