Results 81 to 90 of about 13,917,092 (356)

Three-Dimensional Path Following Control of Underactuated AUV Based on Nonlinear Disturbance Observer and Adaptive Line-of-Sight Guidance

open access: yesIEEE Access
In this study, a backstepping sliding mode control method (NDO-ABSC) based on nonlinear disturbance observer (NDO) and adaptive line-of-sight guidance (ALOS) is proposed to address the three-dimensional path following control problem of underactuated ...
Long He   +5 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

METAL LINE DETECTION: A NEW SENSORY SYSTEM FOR LINE FOLLOWING MOBILE ROBOT [PDF]

open access: yes, 2014
This paper presents a new type of line following robot that uses metal sensor to detect metal line and maneuver around based on that line. The paper focused on developing the hardware model of automated guide vehicle (AGV) system and integrating it ...
Kamarudin, Muhammad Nizam   +5 more
core  

Skin-derived dendritic cells acquire and degrade the scrapie agent following in vitro exposure

open access: yes, 2005
The accumulation of the scrapie agent in lymphoid tissues following inoculation via the skin is critical for efficient neuroinvasion, but how the agent is initially transported from the skin to the draining lymph node is not known. Langerhans cells (LCs)
Hopkins, John   +5 more
core   +1 more source

2D-STRAIGHT LINE PATH FOLLOWING AND NUMERICAL SIMULATION

open access: yesHavacılık ve Uzay Teknolojileri Dergisi, 2018
In this paper, a two-dimensional-straight-line path following methodology for an unmanned aircraft is developed. With the developed algorithm, the unmanned aerial vehicle is made to converge to a predefined path, and then to follow a virtual target on ...
Zafer Öznalbant   +2 more
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Finite-Time Line-of-Sight Guidance-Based Path-Following Control for a Wire-Driven Robot Fish

open access: yesBiomimetics
This paper presents an adaptive line-of-sight (LOS) guidance method, incorporating a finite-time sideslip angle observer to achieve precise planar path tracking of a bionic robotic fish driven by LOS.
Yuyang Mo   +4 more
doaj   +1 more source

MicroRNA Expression Profiling of Pancreatic Cancer Cell Line L3.6p1 Following B7-H4 Knockdown

open access: yesCellular Physiology and Biochemistry, 2017
Background/Aims: Co-stimulating molecule B7-H4 regulates T cell-mediated immune responses, participates in tumor immune escape, and promotes the proliferation and metastasis of pancreatic cancer cells.
Yun Qian   +10 more
doaj   +1 more source

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