Results 111 to 120 of about 378,755 (307)

Bulk and surface symmetry energy for the nuclei far from the valley of stability [PDF]

open access: yesЯдерна фізика та енергетика, 2007
The direct variational method have been applied to the calculation of the symmetry energy for medium and heavy nuclei. The functional of energy of the Thomas - Fermi approximation with the effective Skyrme forces have been used.
V. M. Kolomietz, A. I. Sanzhur
doaj  

Portuguese Timor [cartographic material] : showing telephone systems (Magneto, Earth-return circuits) /

open access: yes, 1942
Map of Portuguese Timor showing telephone systems in use during World War II.; In lower right corner: LRW.; "The Atapoepoe-Batugade line was the only line connecting Dutch and Portugese systems."; Also available online http://nla.gov.au/nla.map ...
Allied Land Forces. L.H.Q. Cartographic Company.
core  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Research on Tooth Positioning and Mechanical Properties of Flexspline Tooth Rings with Harmonic Gear Clearance Assembly

open access: yesJixie chuandong, 2022
The current theory considers that the shape of the deformed flexspline tooth ring neutral line is an isometric line of the cam, which ignores the effect of fit clearance and neutral line's elongation.
Xing Jingzhong   +3 more
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

On Plastic Design of Rotating Complex Machine Elements

open access: yesEngineering Transactions, 1992
The differential relations (analoguous to Henecky equations) along slip-lines in the presence of body forces are formulated. These relations may be used in constructing stress fields for plastic design of various machine elements undergoing large body ...
W. Zowczak
doaj  

Wave forces on cylindrical piles and pile groups : a critical review

open access: yes, 1990
Includes bibliography.This thesis is a critical review of methods of predicting wave forces on vertical piles or groups of piles. It assigns different force prediction theories to different situations or flow regimes and analyses their advantages and ...
Shaul, Robert
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Method of Calculating the Dynamic Loads from the After-Effects of Shock Capture of Metal by Rolls of Blooming Mill

open access: yesМеханика машин, механизмов и материалов, 2019
The method of determining the force factors from the dynamic aftereffect of the shock at capture of metal by rolls of blooming mill is introduced. The differential equations of motion for the main line of the blooming mill are composed taking into ...
Tamaz M. Natriashvili, Slava A. Mebonia
doaj  

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