Results 91 to 100 of about 5,599,027 (309)
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Desert training center and California-Arizone maneuver area. Army Ground Forces Study no. 15.
, 2020 The history of the Army Ground Forces as a command was prepared during the course of the war and completed immediately thereafter. The studies prepared in Headquarters, Army Ground Forces, were written by professional historians, three of whom served as
Historical Section, Army Ground Forces; Meller, Sidney L.
core
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Bulk and surface symmetry energy for the nuclei far from the valley of stability [PDF]
Ядерна фізика та енергетика, 2007 The direct variational method have been applied to the calculation of the symmetry energy for medium and heavy nuclei. The functional of energy of the Thomas - Fermi approximation with the effective Skyrme forces have been used.
V. M. Kolomietz, A. I. Sanzhur
doaj
Loyalty Islands [cartographic material] /
, 1943 Relief shown by hachures.; Includes map index and declination diagram.; Map series of Loyalty Islands showing grass, wooded and cultivated lands, woodlands, plantation, corals, ridges and peaks, bluffs, roads, trails, marshes, villages, brushes, and ...
United States. Army Air Forces.
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
When contact lines remember: Surface charge and the evolving interaction with defects
DropletThe motion of contact line plays a crucial role in both natural phenomena and industrial processes. While it is well known that surface defects influence contact line dynamics, we demonstrate that their impact depends not only on geometry, size, and ...
Yaolei Xiang +4 more
doaj +1 more source
[Central America] : father Neptune presenteth ye Grace Line fleet to ye olde Spanish Main
, 2016 1 Mapa, color. - Mapa pictòric. - `... The informative interest of ths carte is historical and topograpical yet it is rendered in the manner humorous...`.
Grace Line [Companyia naviera]
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source