Results 81 to 90 of about 7,360,893 (335)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Wave hydrodynamic forces over mooring lines on floating offshore wind turbines

Ocean Engineering, 2020
The mooring loading of floating offshore wind turbines are mainly induced by the platform motions through the fairleads. The dynamic analysis usually only considers the hydrodynamic forces over the mooring by the motion of the line disregarding the wave ...
P. Trubat, C. Molins, X. Gironella
semanticscholar   +1 more source

Contact Angle Profiles for Droplets on Omniphilic Surfaces in the Presence of Tangential Forces

Colloids and Interfaces, 2019
In real life, sessile droplets usually have a three-dimensional shape, making it difficult to understand their forced wetting behavior, both from an experimental and a theoretical perspective.
Margaritis Kostoglou, Thodoris Karapantsios   +1 more
doaj   +1 more source

Critical Casimir Effect in 3He-4He films

, 2005
Universal aspects of the thermodynamic Casimir effect in wetting films of 3He-4He mixtures near their bulk tricritical point are studied within suitable models serving as representatives of the corresponding universality class.
, A Maciołek, Crisanti A., Diehl H. W., Fisher M. E., Garcia R., Indekeu J., Krech M., Krech M., Krech M., Lawrie D., S Dietrich   +11 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Nuclear rupture induced by capillary constriction forces promotes differential effects on metastatic and normal breast cells

Scientific Reports
During metastatic dissemination, circulating tumour cells (CTCs) enter capillary beds, where they experience mechanical constriction forces. The transient and persistent effects of these forces on CTCs behaviour remain poorly understood.
Julia Perea Paizal, Sam H. Au, Chris Bakal   +2 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Vortex-Induced Vibration Tests of a Marine Growth Wrapped Cylinder at Subcritical Reynolds Number

MATEC Web of Conferences, 2017
Vortex Induced Vibrations (VIV) may cause great damage to deep water risers. Estimation of accurate hydrodynamic coefficients and response amplitudes for fouled tubular cylinders subjected to VIVs is a complex task.
Kurian V. J., Al-Yacouby A. M., Khir A. R. M.   +2 more
doaj   +1 more source

Forces at superhydrophobic and superamphiphobic surfaces

, 2020
Forces exerted at surfaces and interphases due to formation of gaseous (air or vapor) bridges describe the extreme liquid repellence in superhydrophobicity (SH) and amphiphobicity.
Mimmi Eriksson, A. Swerin
semanticscholar   +1 more source