Results 101 to 110 of about 5,298,176 (299)

Pre-enriched, not primordial ellipticals

, 1997
We follow the chemical evolution of a galaxy through star formation and its feedback into the inter-stellar medium, starting from primordial gas and allowing for gas to inflow into the region being modelled. We attempt to reproduce observed spectral line-
Proctor, R. N., Sansom, A. E.
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

3D NLTE spectral line formation of lithium in late-type stars. [PDF]

Mon Not R Astron Soc, 2021
Wang EX, Nordlander T, Asplund M, Amarsi AM, Lind K, Zhou Y.   +5 more
europepmc   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The formation of IRIS diagnostics I. A quintessential model atom of Mg II and general formation properties of the Mg II h&k lines

, 2013
NASA's Interface Region Imaging Spectrograph (IRIS) space mission will study how the solar atmosphere is energized. IRIS contains an imaging spectrograph that covers the Mg II h&k lines as well as a slit-jaw imager centered at Mg II k.
Carlsson, M., de Pontieu, B., Leenaarts, J., Pereira, T. M. D., Uitenbroek, H.   +4 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

<3D> NLTE line formation in the atmospheres of red supergiants

, 2013
Red supergiants with their enormous brightness at J-band are ideal probes of cosmic chemical composition. It is therefore crucial to have realistic models of radiative transfer in their atmospheres, which will permit determination of abundances accurate ...
Bergemann, Maria, Chiavassa, Andrea, Davies, Ben, Gazak, Zach, Kudritzki, Rolf P., Plez, Bertrand   +5 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Forced spreading over superhydrophobic and copper surfaces

EPJ Web of Conferences, 2017
Dynamic spreading over superhydrophobic and copper surfaces was studied experimentally under the condition of contact line movement with speed greater than 1 mm/sec.
Feoktistov Dmitry, Ponomarev Konstantin, Batishcheva Kseniya   +2 more
doaj   +1 more source