Results 121 to 130 of about 2,098,248 (309)

Non-LTE Line Formation in the Near-IR: Hot Stars

open access: yes, 2010
Line-formation calculations in the Rayleigh-Jeans tail of the spectral energy distribution are complicated by an amplification of non-LTE effects.
N. Przybilla
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Spectral line-by-line pulse shaping of on-chip microresonator frequency combs

open access: yes, 2011
Recently, on-chip comb generation methods based on nonlinear optical modulation in ultrahigh-quality-factor monolithic microresonators have been demonstrated, where two pump photons are transformed into sideband photons in a four-wave-mixing process ...
Lei Chen   +15 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Forecasting the Cross Correlation of Terahertz Intensity Mapper [C ii] Line Intensity Maps with Euclid Galaxies

open access: yesThe Astrophysical Journal
We forecast that the Terahertz Intensity Mapper (TIM) cross-correlated with Euclid’s Deep Field Fornax (EDF-F), TIM × EDF-F, will detect the [C ii ]-galaxy cross-power spectrum at a median redshift of 1.1 with ≳7 σ confidence.
Justin S. Bracks   +26 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Accelerating 3D non-LTE synthesis with graph neural networks

open access: yesAstronomy & Astrophysics
Context. Spectropolarimetric interpretation of chromospheric lines requires solving the radiative transfer problem under non-local thermodynamic equilibrium (NLTE) conditions.
Vicente Arévalo A.   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Exploring the origins of high-velocity features in SNe Ia with the spectral synthesis code TARDIS

open access: yesAstronomy & Astrophysics
Appearing as secondary higher-velocity absorption components, high-velocity features (HVFs) have been observed in several absorption lines in many Type Ia supernovae (SNe Ia). The frequency and ubiquity of these components in silicon and calcium features
Harvey L.   +10 more
doaj   +1 more source

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