Results 101 to 110 of about 10,056,652 (288)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Influence of line isolation overlappings on formation of lightning overvoltages [PDF]

Vestnik MGTU, 2015
The model of substation protection against lightning waves with considered multiple overlappings of line isolation has been presented. Influence of multiple overlapping of isolation on line support on formation of lightning overvoltages has been shown ...
Antropov I. M., Efimov B. V. , Nevretdinov Yu. M.   +2 more
doaj  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Formation professionnelle

, 1993
Publ.
Centre européen pour le développement de la formation professionnelle
core   +2 more sources

Iron He-triplet signatures of shocks in the hottest galaxy clusters

Astronomy & Astrophysics
A merger of clusters naturally drives shocks with Mach number ℳ ≲ 3 in the intracluster medium (ICM). This process creates several distinct signatures, including sharp surface-brightness “edges”, temperature, and gas-velocity jumps.
Churazov Eugene, Ralchenko Yuri, Khabibullin Ildar I., Raymond John C., Heinrich Annie, Zhuravleva Irina, van Weeren Reinout J., Zhang Congyao   +7 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Formation professionnelle

, 1995
Publ. comme no 7, janv./avril 1996 de la revue Formation professionnelleL'évolution des fonctions de la formation -- Enseignement ouvert -- Modularisation : aspects du débat en Allemagne et au Royaume-Uni -- Développement de compétences et organisation ...
Centre européen pour le développement de la formation professionnelle
core   +1 more source

Trace the Self-gravitating Gas Using CO Isotopologues

The Astrophysical Journal
Recent studies have shown that the star formation rate (SFR) correlates tightly and linearly with the mass of gravitationally bound gas, which can be delineated from the power-law tail of the column-density probability distribution function ( N -PDF ...
Linjing Feng, Jingwen Wu, Sihan Jiao, Zhi-Yu Zhang, Junzhi Wang, Chao-Wei Tsai, Di Li, Hauyu Baobab Liu, Yan Sun, Neal J. Evans II, Yuxin Lin, Hao Ruan, Fangyuan Deng, Yuanzhen Xiong, Ruofei Zhang   +14 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source