Results 91 to 100 of about 118,308 (264)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Design and Analysis of the Gear Conjugate Profile based on the Sine- curved Benchmark Tooth Profile
Jixie chuandong, 2015 The benchmark tooth profile of gear cutter is designed to a sine curve. The gear conjugate profile is solved by tooth profile normal method. The meshing line,curvature and relative sliding ratio are analyzed,and then the bending strength is analyzed ...
Cui Gaoshang, Fan Yuanxun
doaj
Straight-line string with curvature
, 1995 Classical and quantum solutions for the relativistic straight-line string with arbitrary dependence on the world surface curvature are obtained. They differ from the case of the usual Nambu-Goto interaction by the behaviour of the Regge trajectory which in general can be nonlinear.
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Generalized Dupin Cyclides with Rational Lines of Curvature [PDF]
, 2012 Dupin cyclides are algebraic surfaces of order three and four whose lines of curvature are circles. These surfaces have a variety of interesting properties and are aesthetic from a geometric and algebraic viewpoint. Besides their special property with respect to lines of curvature they appear as envelopes of one-parameter families of spheres in a ...
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Single-valuedness of the AdS Veneziano amplitude
Journal of High Energy PhysicsWe consider the Veneziano amplitude for the scattering of gluons in type IIB string theory on AdS 5 × S 5/ℤ 2 in the presence of D7 branes. On general grounds curvature corrections around flat space can be thought of as arising from the extra insertion ...
Luis F. Alday, Tobias Hansen
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Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Applied SciencesThis study aimed to determine whether there are relationships between vertical facial patterns, cervical posture, and cervical curvature types. Ninety-two adult females with skeletal Class I relationships were retrospectively analyzed and divided into ...
Jeongeun Chang +7 more
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On the Curvature of the Level Lines of a Harmonic Function [PDF]
Proceedings of the American Mathematical Society, 1963 Jerrard, R. P., Rubel, L. A.
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